Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM6A | O15550 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22774031 | 0.81 | GSK3B (0.38) | EGFREGLN1PDGFRACDK5TYRO3 | |
| SCHEMBL29576495 | 0.81 | GSK3B (0.38) | EGFREGLN1PDGFRACDK5TYRO3 | |
| Hydrochloric Acid SCHEMBL29744368 | 0.80 | GSK3B (0.37) | EGFREGLN1PDGFRACDK5TYRO3 | |
| SCHEMBL1490718 | 0.78 | ALK (0.50) | SLC22A12ALKEGFRGAKNCF1 | |
| SCHEMBL9397293 | 0.73 | SLC22A12 (0.45) | SLC22A12ALKEGFRGAKKDM4E | |
| SCHEMBL16292269 | 0.69 | LMNA (0.39) | GSK3BMAPK8KDM4EKDM6AKDM4A | |
| SCHEMBL30186358 | 0.69 | KDM4E (0.44) | GSK3BKDM4EKDM6AKDM4ACYP2C9 | |
| SCHEMBL23497809 | 0.68 | ALDH1A1 (0.43) | EGLN1GSK3BKDM4E | |
| SCHEMBL15992161 | 0.67 | KDM4E (0.46) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL360254 | 0.66 | SLC22A12 (0.51) | SLC22A12ALKGAKNCF1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021116446-A1 | FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-06-17 | — | — | WO | disclosed |