Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23500680 | 0.80 | LMNA (0.56) | ALOX15ALDH1A1L3MBTL1KDM4EKMT2A | |
| SCHEMBL31084231 | 0.77 | ALOX15 (0.51) | ALOX15HTTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL15655786 | 0.77 | ALDH1A1 (0.45) | ALOX15HTTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3635127 | 0.75 | KDM4E (0.65) | ALOX15HTTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL26123183 | 0.73 | ALOX15 (0.61) | ALOX15HTTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL30427495 | 0.73 | ALOX15 (0.61) | ALOX15HTTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL247859 | 0.72 | L3MBTL1 (0.48) | ALOX15HTTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3307271 | 0.72 | ALOX15 (0.49) | ALOX15HTTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL31345639 | 0.72 | ALOX15 (0.49) | ALOX15HTTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL28558680 | 0.72 | ALOX15 (0.49) | ALOX15HTTALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115225-A1 | PYRAZOLE-CONTAINING POLYCYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2021-06-17 | — | — | WO | disclosed |