Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933872 | 1.00 | POLB (0.44) | POLBHCAR2ALDH1A1MEN1KMT2A | |
| SCHEMBL29933997 | 0.87 | PKM (0.43) | ALDH1A1MEN1KMT2AHTTRAB9A | |
| SCHEMBL29934060 | 0.80 | TAS1R3 (0.47) | MEN1KMT2AKDM4E | |
| SCHEMBL29934040 | 0.75 | POLB (0.44) | POLBHCAR2ALDH1A1KDM4EHTT | |
| SCHEMBL23501594 | 0.75 | POLB (0.44) | POLBHCAR2ALDH1A1KDM4EHTT | |
| SCHEMBL7968434 | 0.68 | MRGPRX4 (0.49) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3258577 | 0.68 | ALDH1A1 (0.52) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27637429 | 0.68 | MRGPRX4 (0.51) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27735801 | 0.68 | MAPT (0.32) | POLBHCAR2KDM4EHTTRAB9A | |
| SCHEMBL23501607 | 0.68 | HDAC8 (0.53) | POLBHCAR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |
| WO-2021117846-A1 | COMPOUND SERVING AS PDGF RECEPTOR KINASE INHIBITOR, AND COMPOSITION | 日本新薬株式会社 | 2021-06-17 | — | — | WO | disclosed |