Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27637429 | 0.88 | MRGPRX4 (0.51) | ALDH1A1MRGPRX4TSHRMEN1KMT2A | |
| SCHEMBL2809375 | 0.86 | MRGPRX4 (0.48) | ALDH1A1MRGPRX4TSHRRXRASMN1; SMN2 | |
| SCHEMBL11427122 | 0.86 | PKM (0.52) | ALDH1A1MRGPRX4TSHRMEN1KMT2A | |
| SCHEMBL27561164 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MRGPRX4TSHRKMT2ARXRA | |
| SCHEMBL20045101 | 0.84 | MRGPRX4 (0.49) | ALDH1A1MRGPRX4TSHRMEN1KMT2A | |
| SCHEMBL2382916 | 0.84 | MRGPRX4 (0.49) | ALDH1A1MRGPRX4TSHRMEN1KMT2A | |
| SCHEMBL7968434 | 0.84 | MRGPRX4 (0.49) | ALDH1A1MRGPRX4TSHRMEN1KMT2A | |
| SCHEMBL7945742 | 0.84 | MRGPRX4 (0.52) | ALDH1A1MRGPRX4TSHRMEN1KMT2A | |
| SCHEMBL2807448 | 0.83 | RARB (0.51) | ALDH1A1MRGPRX4TSHRMEN1KMT2A | |
| SCHEMBL2054466 | 0.83 | PKM (0.53) | ALDH1A1TSHRMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818799-A | COORDINATION CATALYST ALSO COMPRISING AN ALKYL-ALUMINUM-ANTIOXIDENT TO RELEASE THE ANTIOXIDANT IN SITU | SHELL OIL COMPANY (US) | 1989-04-04 | — | — | US | claimed |
| US-4276193-A | MAGNESIUM DIHALIDE CARRIER, CATALYST COMPRISING AN ELECTRON DONOR, TITANIUM TETRACHLORIDE REDUCED WITH AN ORGANOALUMINUM HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-30 | — | — | US | claimed |
| CN-112759528-B | Imine ester compound and preparation method thereof | 中国石油化工股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-112759677-B | Solid catalyst component for olefin polymerization, catalyst and application thereof | 中国石油化工股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-112759676-B | Solid catalyst component for preparing polyolefin, catalyst and application thereof | 中国石油化工股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| US-20230190946-A1 | COMPOUNDS | ZEALAND PHARMA A/S (DK) | 2023-06-22 | — | — | US | disclosed |
| WO-2022085505-A1 | METHOD OF PRODUCING Mg-CONTAINING PARTICLES | 東邦チタニウム株式会社 | 2022-04-28 | — | — | WO | disclosed |
| US-11154556-B2 | Methods of treating solid tumors with CCR2 antagonists | CHEMOCENTRYX, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-10464934-B2 | Substituted tetrahydropyrans as CCR2 modulators | CHEMOCENTRYX, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| US-20190209573-A1 | METHODS OF TREATING SOLID TUMORS WITH CCR2 ANTAGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-07-11 | — | — | US | disclosed |
| US-20180098952-A1 | INACTIVATORS OF TOXOPLASMA GONDII ORNITHINE AMINOTRANSFERASE FOR TREATING TOXOPLASMOSIS AND MALARIA | NORTHWESTERN UNIVERSITY (US) | 2018-04-12 | — | — | US | disclosed |
| US-4472524-A | COORDINATION CATALYSTS | MONTEDISON S.P.A. (IT) | 1984-09-18 | — | — | US | disclosed |
| EP-0086471-A2 | Components and catalysts for the polymerization of olefins | Montedison S.p.A. (IT) | 1983-08-24 | — | — | EP | disclosed |
| EP-0086472-A2 | Catalyst for the polymerization of olefins | Montedison S.p.A. (IT) | 1983-08-24 | — | — | EP | disclosed |
| EP-0086473-A2 | Components and catalysts for the polymerization of olefins | Montedison S.p.A. (IT) | 1983-08-24 | — | — | EP | disclosed |
| EP-0008764-B1 | PROCESS FOR THE PREPARATION OF A CATALYST ON A SOLID CARRIER AND ITS USE IN THE POLYMERISATION OF PROPYLENE | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| US-4276193-A | MAGNESIUM DIHALIDE CARRIER, CATALYST COMPRISING AN ELECTRON DONOR, TITANIUM TETRACHLORIDE REDUCED WITH AN ORGANOALUMINUM HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-30 | — | — | US | disclosed |
| EP-0008764-A2 | Process for the preparation of a catalyst on a solid carrier and its use in the polymerisation of propylene | BAYER AG (DE) | 1980-03-19 | — | — | EP | disclosed |
| US-4140859-A | Dilithiated 2-(o-tolyl)-2-imidazolines | SANDOZ, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4101553-A | Imidazo[2,1-a]isoquinolines | SANDOZ, INC. (US) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464934-B2 | Substituted tetrahydropyrans as CCR2 modulators | CCR2, CCR1, CCR5 | ALDH1A1 1316/4885MRGPRX4 167/4885TSHR 722/4885 |
| US-20190209573-A1 | METHODS OF TREATING SOLID TUMORS WITH CCR2 ANTAGONISTS | CCR2, CXCR2, CCRL2 | ALDH1A1 3105/4885MRGPRX4 81/4885TSHR 356/4885 |
| US-20180098952-A1 | INACTIVATORS OF TOXOPLASMA GONDII ORNITHINE AMINOTRANSFERASE FOR TREATING TOXOPLASMOSIS AND MALARIA | OAT, OTC, ABAT | ALDH1A1 163/4885MRGPRX4 2928/4885TSHR 1613/4885 |
| US-20230190946-A1 | COMPOUNDS | ITGB7, SCN7A, ITGB4 | ALDH1A1 333/4885MRGPRX4 146/4885TSHR 2267/4885 |
| US-11154556-B2 | Methods of treating solid tumors with CCR2 antagonists | CCR2, CXCR2, CCRL2 | ALDH1A1 3105/4885MRGPRX4 81/4885TSHR 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.