Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23506243 | 0.88 | LMNA (0.46) | CTSLCTSBCTSKNOD1 | |
| SCHEMBL23506235 | 0.88 | LMNA (0.46) | CTSLCTSBCTSKNOD1 | |
| SCHEMBL23506325 | 0.85 | — | — | |
| SCHEMBL23506247 | 0.82 | LMNA (0.47) | CTSLCTSB | |
| SCHEMBL23506278 | 0.82 | LMNA (0.47) | CTSLCTSB | |
| SCHEMBL23506361 | 0.81 | MMP13 (0.37) | CTSLCTSBKMT2A | |
| SCHEMBL19606056 | 0.80 | CTSB (0.39) | CTSLCTSB | |
| SCHEMBL23506441 | 0.79 | CTSL (0.48) | CTSLCTSB | |
| SCHEMBL23506336 | 0.78 | CTSL (0.40) | CTSLCTSB | |
| SCHEMBL21702238 | 0.78 | CCKBR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3835296-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-06-16 | — | — | EP | disclosed |