Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353890 | 0.81 | SLC10A2 (0.37) | HTR2CHTR2B | |
| SCHEMBL2354740 | 0.81 | KDM1A (0.32) | — | |
| SCHEMBL2353872 | 0.79 | CXCR2 (0.32) | — | |
| SCHEMBL2355107 | 0.75 | ADRA1D (0.30) | — | |
| SCHEMBL2357167 | 0.73 | ADRA1D (0.37) | MEN1KMT2A | |
| SCHEMBL2347270 | 0.71 | GRIA1 (0.35) | HTR2CTP53 | |
| SCHEMBL2354545 | 0.70 | ADRA1D (0.30) | — | |
| SCHEMBL2354749 | 0.69 | — | — | |
| SCHEMBL21032204 | 0.68 | ADRA1D (0.36) | MEN1KMT2A | |
| SCHEMBL2354707 | 0.68 | CA1 (0.41) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |