SCHEMBL2354545

SCHEMBL2354545

O=S1(=O)CCC(C2CC2)c2cc(Cl)c(Cl)cc21

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2355724 0.87
SCHEMBL2354707 0.80 CA1 (0.41) ADRA1D
SCHEMBL2355589 0.73 ADRA1D (0.40) ADRA1D
SCHEMBL2355322 0.73 ADRA1D (0.45) ADRA1D
SCHEMBL2357167 0.71 ADRA1D (0.37) ADRA1D
SCHEMBL2355107 0.71 ADRA1D (0.30) ADRA1D
SCHEMBL21032204 0.67 ADRA1D (0.36) ADRA1D
SCHEMBL2353872 0.66 CXCR2 (0.32) ADRA1D
SCHEMBL2353940 0.65 GRIA2 (0.48) ADRA1D
SCHEMBL2356693 0.63 ADRA1D (0.30) ADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011083264-A1 THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2011-07-14 WO claimed
WO-2011083264-A1 THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2011-07-14 WO disclosed