Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23508645 | 0.75 | OTUD7B (0.40) | SIGMAR1DRD2AVPR1AOTUD7B | |
| SCHEMBL15935918 | 0.74 | KCNH2 (0.39) | SIGMAR1DRD2AVPR1A | |
| SCHEMBL23508736 | 0.74 | ALDH1A1 (0.33) | SIGMAR1 | |
| SCHEMBL12175572 | 0.71 | AVPR1A (0.45) | SIGMAR1DRD2AVPR1A | |
| SCHEMBL23508956 | 0.69 | CNR1 (0.34) | SIGMAR1 | |
| SCHEMBL16173452 | 0.67 | OTUD7B (0.35) | SIGMAR1DRD2OTUD7B | |
| SCHEMBL16274418 | 0.65 | SIGMAR1 (0.47) | SIGMAR1DRD2 | |
| SCHEMBL19649608 | 0.64 | AVPR1A (0.63) | SIGMAR1DRD2AVPR1A | |
| SCHEMBL13162862 | 0.64 | CHRNB2 (0.48) | SIGMAR1DRD2OTUD7B | |
| SCHEMBL15935916 | 0.62 | FGFR1 (0.38) | OTUD7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115286-A1 | SIX-MEMBERED AND FIVE-MEMBERED AROMATIC RING DERIVATIVE CONTAINING NITROGEN HETEROATOMS WHICH CAN BE USED AS SHP2 INHIBITOR | 成都倍特药业股份有限公司 | 2021-06-17 | — | — | WO | disclosed |