Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17174033 | 0.88 | RARB (0.50) | RARBKDM4ERARALMNAL3MBTL1 | |
| SCHEMBL23512464 | 0.85 | ALOX15 (0.55) | KDM4ERXRARXRBALDH1A1SMN1; SMN2 | |
| SCHEMBL24897600 | 0.84 | L3MBTL1 (0.60) | RARBRARAL3MBTL1HDAC1HDAC2 | |
| SCHEMBL24674912 | 0.84 | PLA2G4B (0.54) | KDM4ELMNAMAPTALDH1A1HPGD | |
| SCHEMBL2116281 | 0.83 | ALOX15 (0.54) | RARBL3MBTL1HDAC1HDAC2MAPT | |
| SCHEMBL17941045 | 0.83 | TDP1 (0.56) | RARBLMNAL3MBTL1MAPTRAB9A | |
| SCHEMBL24934781 | 0.81 | KDM4E (0.49) | RARBKDM4ELMNAL3MBTL1RXRA | |
| SCHEMBL22932079 | 0.81 | SMN1; SMN2 (0.67) | RARBKDM4ERXRARXRBHDAC1 | |
| SCHEMBL22932078 | 0.81 | ALDH1A1 (0.50) | RARBKDM4ERARAL3MBTL1RXRA | |
| SCHEMBL809992 | 0.80 | ALOX15 (0.61) | L3MBTL1MAPTALDH1A1SMN1; SMN2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132561-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |