SCHEMBL23514435

SCHEMBL23514435

CN(C)C1CCN(C(=O)[C@@H](N)CSSC[C@H](N)C(=O)N2CCC(N(C)C)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 2/20 0.44
OPRD1 P41143 6/20 0.40
FNTA P49354 2/20 0.37
FNTB P49356 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
DPP7 Q9UHL4 3/20 0.36
DPP4 P27487 1/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23514434 1.00 L3MBTL3 (0.44) L3MBTL3OPRD1FNTAFNTBL3MBTL1
SCHEMBL23514440 0.94 L3MBTL3 (0.40) L3MBTL3OPRD1FNTAFNTBL3MBTL1
SCHEMBL15045182 0.78 L3MBTL3 (0.50) L3MBTL3L3MBTL1DPP7DPP4DPP8
SCHEMBL19502759 0.78 L3MBTL3 (0.50) L3MBTL3L3MBTL1DPP7DPP4DPP8
SCHEMBL15853678 0.76 DPP7 (0.41) DPP7DPP4DPP8
SCHEMBL19982000 0.76 L3MBTL3 (0.47) L3MBTL3OPRD1DPP7DPP4DPP8
SCHEMBL23514532 0.75 DPP8 (0.49) L3MBTL3L3MBTL1DPP8
SCHEMBL23514531 0.75 DPP8 (0.49) L3MBTL3L3MBTL1DPP8
SCHEMBL22917833 0.75 CYP1A2 (0.42)
SCHEMBL15853672 0.75 CYP1A2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230043330-A1 Cystine Diamide Analogs For Cystinuria RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-02-09 US disclosed
WO-2021119475-A1 CYSTINE DIAMIDE ANALOGS FOR CYSTINURIA RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2021-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230043330-A1 Cystine Diamide Analogs For Cystinuria CTH, CBS, SLC7A11 L3MBTL3 2947/4885OPRD1 2271/4885FNTA 3161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.