Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 8/20 | 0.41 |
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19502759 | 1.00 | L3MBTL3 (0.50) | L3MBTL3MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19982000 | 0.86 | L3MBTL3 (0.47) | L3MBTL3MEN1ALDH1A1KMT2ADPP4 | |
| SCHEMBL4546641 | 0.85 | L3MBTL3 (0.53) | L3MBTL3MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL10160258 | 0.81 | L3MBTL3 (0.50) | L3MBTL3MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL22629569 | 0.79 | ALDH1A1 (0.66) | MEN1ALDH1A1KMT2ASMYD3DPP4 | |
| SCHEMBL30364025 | 0.79 | SMYD3 (0.52) | MEN1ALDH1A1KMT2ASMYD3DPP4 | |
| SCHEMBL23514435 | 0.78 | L3MBTL3 (0.44) | L3MBTL3L3MBTL1DPP4DPP7DPP8 | |
| SCHEMBL23514434 | 0.78 | L3MBTL3 (0.44) | L3MBTL3L3MBTL1DPP4DPP7DPP8 | |
| SCHEMBL15247318 | 0.77 | SMYD3 (0.49) | MEN1ALDH1A1KMT2ASMYD3DPP4 | |
| SCHEMBL25068495 | 0.77 | SMYD3 (0.49) | MEN1ALDH1A1KMT2ASMYD3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464273-B9 | IMIDAZOLONE COMPOUNDS AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | CHIESI FARM SPA (IT) | 2020-10-21 | — | — | EP | disclosed |
| EP-3464273-B1 | IMIDAZOLONE COMPOUNDS AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | CHIESI FARM SPA (IT) | 2020-04-08 | — | — | EP | disclosed |
| EP-3464268-B1 | NOVEL COMPOUNDS | CHIESI FARM SPA (IT) | 2020-03-11 | — | — | EP | disclosed |
| US-10172830-B2 | Pyrazolone compounds having human neutrophil elastase inhibitory properties | CHIESI FARMACEUTICI S.P.A. (IT) | 2019-01-08 | — | — | US | disclosed |
| US-10023558-B2 | Compounds | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-07-17 | — | — | US | disclosed |
| US-20180009787-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-01-11 | — | — | US | disclosed |
| US-20170340611-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-11-30 | — | — | US | disclosed |
| US-9802919-B1 | Compounds | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-10-31 | — | — | US | disclosed |
| EP-2604601-A1 | HETERO RING COMPOUND | Astellas Pharma Inc. (JP) | 2013-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023558-B2 | Compounds | SERPINB1, ELANE, MPO | L3MBTL3 3802/4885MEN1 3964/4885ALDH1A1 79/4885 |
| US-20170340611-A1 | NOVEL COMPOUNDS | SERPINB1, ELANE, MPO | L3MBTL3 4541/4885MEN1 4540/4885ALDH1A1 88/4885 |
| US-20180009787-A1 | NOVEL COMPOUNDS | SERPINB1, ELANE, MPO | L3MBTL3 3867/4885MEN1 4581/4885ALDH1A1 263/4885 |
| US-10172830-B2 | Pyrazolone compounds having human neutrophil elastase inhibitory properties | SERPINB1, ELANE, EPX | L3MBTL3 4588/4885MEN1 4112/4885ALDH1A1 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.