Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23527323 | 0.88 | ALDH1A1 (0.49) | ALDH1A1KDM4EALOX15HSD17B10POLB | |
| SCHEMBL857196 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4EALOX15HSD17B10POLB | |
| SCHEMBL23527306 | 0.73 | ADORA2A (0.44) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL1710002 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4EALOX15HSD17B10POLB | |
| SCHEMBL10882291 | 0.71 | LMNA (0.59) | ALDH1A1KDM4EALOX15HSD17B10POLB | |
| SCHEMBL23527338 | 0.70 | PTGES (0.59) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL5793312 | 0.69 | TDP1 (0.59) | ALDH1A1KDM4EALOX15HSD17B10POLB | |
| SCHEMBL13831223 | 0.68 | MAPT (0.40) | ALDH1A1HSD17B10POLBTP53HPGD | |
| SCHEMBL13831537 | 0.68 | SMN1; SMN2 (0.52) | ALDH1A1HSD17B10POLBHPGDTSHR | |
| SCHEMBL24380353 | 0.66 | POLB (0.47) | ALDH1A1KDM4EALOX15HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600704-B2 | Substituted 1,2,4-triazoles and methods of use | STINGINN LLC (US) | 2026-04-14 | — | — | US | disclosed |
| EP-4075980-B1 | SUBSTITUTED 1,2, 4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| US-20250163005-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2025-05-22 | — | — | US | disclosed |
| US-12134605-B2 | Substituted 1,2,4-triazoles and methods of use | STINGINN, LLC (US) | 2024-11-05 | — | — | US | disclosed |
| US-20240262796-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2024-08-08 | — | — | US | disclosed |
| US-20210188786-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2021-06-24 | — | — | US | disclosed |
| US-20210188786-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2021-06-24 | — | — | US | disclosed |
| WO-2021127282-A1 | SUBSTITUTED 1,2, 4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2021-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188786-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STING1, IRF3, CGAS | ALDH1A1 3318/4885KDM4E 1857/4885ALOX15 2686/4885 |
| US-12134605-B2 | Substituted 1,2,4-triazoles and methods of use | STING1, IRF3, CGAS | ALDH1A1 3318/4885KDM4E 1857/4885ALOX15 2686/4885 |
| US-12600704-B2 | Substituted 1,2,4-triazoles and methods of use | STING1, IRF3, MAVS | ALDH1A1 3818/4885KDM4E 4080/4885ALOX15 3020/4885 |
| US-20250163005-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STING1, IRF3, CGAS | ALDH1A1 3318/4885KDM4E 1857/4885ALOX15 2686/4885 |
| US-20240262796-A1 | SUBSTITUTED 1,2,4-TRIAZOLES AND METHODS OF USE | STING1, IRF3, CGAS | ALDH1A1 3318/4885KDM4E 1857/4885ALOX15 2686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.