Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29931795 | 0.98 | RAB9A (0.49) | RAB9ANPC1TNFNOD1LMNA | |
| SCHEMBL29932025 | 0.98 | RAB9A (0.49) | RAB9ANPC1TNFNOD1LMNA | |
| SCHEMBL29782844 | 0.81 | PGR (0.61) | RAB9ANPC1TNFNOD1LMNA | |
| SCHEMBL4952964 | 0.81 | PGR (0.61) | RAB9ANPC1TNFNOD1LMNA | |
| SCHEMBL3838916 | 0.78 | CA2 (0.60) | ALDH1A1 | |
| SCHEMBL7163455 | 0.78 | RAB9A (0.63) | RAB9ANPC1TNFNOD1LMNA | |
| SCHEMBL10995381 | 0.77 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL12896230 | 0.77 | RAB9A (0.47) | RAB9ANPC1TNFNOD1LMNA | |
| SCHEMBL10741172 | 0.76 | PSIP1 (0.48) | ALDH1A1 | |
| SCHEMBL17287517 | 0.73 | CA1 (0.45) | LMNAALDH1A1MAPTPGRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |