Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536620 | 0.78 | HTR6 (0.49) | L3MBTL1HTR6 | |
| SCHEMBL23536654 | 0.78 | SCN5A (0.38) | ALDH3A1HTTHTR6TP53TSHR | |
| SCHEMBL23536676 | 0.69 | HTR6 (0.38) | HTTHTR6TP53TSHRSMN1; SMN2 | |
| SCHEMBL21222781 | 0.69 | ALDH3A1 (0.47) | ALDH3A1POLBHTTNOD1L3MBTL1 | |
| SCHEMBL23536574 | 0.66 | SLC6A2 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL23536553 | 0.66 | MAPT (0.38) | HTTHTR6HTR1AHTR7ALDH1A1 | |
| SCHEMBL23536590 | 0.65 | MEN1 (0.38) | HTTL3MBTL1ALDH1A1TP53TSHR | |
| SCHEMBL30037609 | 0.64 | ALDH3A1 (0.49) | ALDH3A1POLBHTTNOD1L3MBTL1 | |
| SCHEMBL25552140 | 0.64 | ALDH3A1 (0.49) | ALDH3A1POLBHTTNOD1L3MBTL1 | |
| SCHEMBL25552138 | 0.64 | ALDH3A1 (0.49) | ALDH3A1POLBHTTNOD1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |