Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536744 | 0.78 | ALDH3A1 (0.46) | HTR6L3MBTL1 | |
| SCHEMBL23536538 | 0.77 | HTR6 (0.56) | HTR6CYP3A4CYP2D6KLK7 | |
| SCHEMBL23536654 | 0.76 | SCN5A (0.38) | HTR6CYP3A4 | |
| SCHEMBL23536650 | 0.70 | HTR6 (0.75) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL23536641 | 0.69 | HTT (0.46) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6530503 | 0.68 | CYP3A4 (0.83) | HTR6CYP3A4CYP2D6L3MBTL1CA12 | |
| SCHEMBL23536574 | 0.68 | SLC6A2 (0.40) | — | |
| SCHEMBL23536676 | 0.67 | HTR6 (0.38) | HTR6CYP3A4 | |
| SCHEMBL28018212 | 0.66 | KDM4E (0.68) | HTR6CYP3A4CYP2D6L3MBTL1CA9 | |
| SCHEMBL17394583 | 0.66 | HTR6 (0.57) | HTR6CYP3A4CYP2D6L3MBTL1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |