SCHEMBL2353705

SCHEMBL2353705

[CH2]C(=O)O[SiH2]CCCCCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
TSHR P16473 6/20 0.37
GPR84 Q9NQS5 7/20 0.37
PPARG P37231 7/20 0.37
PPARD Q03181 7/20 0.37
PPARA Q07869 7/20 0.37
HDAC11 Q96DB2 5/20 0.37
PTPN1 P18031 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TLR2 O60603 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
FABP4 P15090 2/20 0.37
SLC22A6 Q4U2R8 1/20 0.37
SLC22A8 Q8TCC7 1/20 0.37
MEN1 O00255 1/20 0.37
ESR1 P03372 1/20 0.37
ALOX15 P16050 1/20 0.37
PDE4A P27815 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2353931 1.00 CES2 (0.38) CES2CES1TSHRGPR84PPARG
SCHEMBL1408890 1.00 CES2 (0.38) CES2CES1TSHRGPR84PPARG
SCHEMBL2354550 0.98 CES2 (0.36) CES2CES1TSHRGPR84PPARG
SCHEMBL1408644 0.91
SCHEMBL2353936 0.81 ALDH1A1 (0.41) CES2CES1TSHRGPR84PPARG
SCHEMBL1408892 0.81 ALDH1A1 (0.41) CES2CES1TSHRGPR84PPARG
SCHEMBL2353709 0.81 ALDH1A1 (0.41) CES2CES1TSHRGPR84PPARG
SCHEMBL6659112 0.79 DGKA (0.45) CES2CES1TSHRGPR84PPARG
SCHEMBL3715430 0.79 TSHR (0.48) CES2CES1TSHRALDH1A1MEN1
SCHEMBL27781005 0.79 TSHR (0.48) CES2CES1TSHRALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912120-A1 ANTIFOULING COATING COMPOSITION Jotun A/S (NO) 2015-09-02 EP disclosed
WO-2014064049-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
WO-2014064048-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed