SCHEMBL2354550

SCHEMBL2354550

[CH2]C(=O)O[SiH2]CCCCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.36
CES1 P23141 4/20 0.36
AKR1B1 P15121 1/20 0.34
TSHR P16473 6/20 0.34
GPR84 Q9NQS5 6/20 0.33
PPARG P37231 6/20 0.33
PPARD Q03181 6/20 0.33
PPARA Q07869 6/20 0.33
HDAC11 Q96DB2 5/20 0.33
ALDH1A1 P00352 2/20 0.33
TLR2 O60603 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
FABP4 P15090 2/20 0.33
PTPN1 P18031 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
NAAA Q02083 1/20 0.33
MEN1 O00255 1/20 0.33
ESR1 P03372 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2353931 0.98 CES2 (0.38) CES2CES1TSHRGPR84PPARG
SCHEMBL1408890 0.98 CES2 (0.38) CES2CES1TSHRGPR84PPARG
SCHEMBL2353705 0.98 CES2 (0.38) CES2CES1TSHRGPR84PPARG
SCHEMBL1408644 0.93
SCHEMBL1471084 0.80 ALDH1A1 (0.43) CES2CES1AKR1B1TSHRGPR84
SCHEMBL1408892 0.78 ALDH1A1 (0.41) CES2CES1TSHRGPR84PPARG
SCHEMBL2353709 0.78 ALDH1A1 (0.41) CES2CES1TSHRGPR84PPARG
SCHEMBL2353936 0.78 ALDH1A1 (0.41) CES2CES1TSHRGPR84PPARG
SCHEMBL9618502 0.78 TSHR (0.52) CES2CES1AKR1B1TSHRALDH1A1
SCHEMBL6659112 0.77 DGKA (0.45) CES2CES1TSHRGPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed