Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.35 |
| ▸ | NNMT | P40261 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28247848 | 0.75 | KMT2A (0.49) | KMT2AAPPSIRT6NNMTP4HTM | |
| SCHEMBL13002904 | 0.68 | KIT (0.53) | KMT2AKITFLT3APPSIRT6 | |
| SCHEMBL5490024 | 0.68 | L3MBTL1 (0.42) | KMT2ATSHR | |
| SCHEMBL29852294 | 0.67 | P4HTM (0.50) | KMT2AAPPNAMPTVNN1OPRM1 | |
| SCHEMBL171039 | 0.65 | KMT2A (0.53) | KMT2ASIRT6NNMTP4HTMADORA3 | |
| SCHEMBL30074643 | 0.65 | KMT2A (0.58) | KMT2AKITFLT3SIRT6NNMT | |
| SCHEMBL319254 | 0.65 | KMT2A (0.58) | KMT2AKITFLT3SIRT6NNMT | |
| SCHEMBL5481193 | 0.65 | ROCK2 (0.30) | ROCK2 | |
| SCHEMBL2793195 | 0.65 | SIRT6 (0.40) | KMT2AAPPSIRT6NNMTPDE4A | |
| SCHEMBL30980810 | 0.65 | VNN1 (0.55) | KMT2AAPPSIRT6NAMPTVNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127459-A1 | GPR139 RECEPTOR MODULATORS | BLACKTHORN THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |