SCHEMBL2354820

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8497646	0.81	LTA4H (0.47)	TLR4TLR2P2RX3HCRTR1HCRTR2
	SCHEMBL8052741	0.80	TLR4 (0.52)	TLR4TLR2P2RX3RAF1KDR
	SCHEMBL8557561	0.76	TLR4 (0.52)	TLR4TLR2P2RX3
	SCHEMBL4686579	0.76	TLR4 (0.52)	TLR4TLR2TSHRSMN1; SMN2P2RX3
	SCHEMBL5431733	0.76	TLR4 (0.52)	TLR4TLR2SMN1; SMN2CTSAHCRTR1
	SCHEMBL7355562	0.76	TLR4 (0.52)	TLR4TLR2SMN1; SMN2P2RX3RAF1
	SCHEMBL12100240	0.76	TLR4 (0.52)	TLR4TLR2SMN1; SMN2P2RX3RAF1
	SCHEMBL9046569	0.76	TLR4 (0.44)	TLR4TLR2P2RX3ALOX5
	SCHEMBL3288907	0.76	MEN1 (0.53)	TLR4TLR2NR1H2NR1H3GPBAR1
	SCHEMBL2110045	0.75	TLR4 (0.49)	TLR4TLR2TSHRSMN1; SMN2HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.