SCHEMBL2355652

SCHEMBL2355652

Cc1ccc(OC(=O)O)c(-c2ccccc2)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.42
FABP4 P15090 2/20 0.39
NCEH1 Q6PIU2 1/20 0.38
ACLY P53396 1/20 0.37
LMNA P02545 3/20 0.37
ALDH1A1 P00352 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
FABP3 P05413 1/20 0.36
FABP5 Q01469 1/20 0.36
RPA1 P27694 1/20 0.36
MCL1 Q07820 1/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28784939 0.88 FABP4 (0.43) PTPN1FABP4ACLYLMNAALDH1A1
SCHEMBL5587781 0.81 PDE4A (0.41) PTPN1FABP4ACLYLMNAALDH1A1
SCHEMBL237314 0.81 FABP4 (0.46) FABP4LMNAALDH1A1RAB9ASMN1; SMN2
SCHEMBL1837252 0.80 MYC (0.41) FABP4LMNAALDH1A1RAB9ASMN1; SMN2
SCHEMBL11226020 0.80 KMT2A (0.36) PTPN1FABP4LMNAALDH1A1RAB9A
SCHEMBL5589914 0.79 PDE4B (0.39) ACLYLMNANPC1MAPTHPGD
SCHEMBL8335880 0.78 FABP3 (0.43) FABP4ALDH1A1RAB9AKDM4ENPC1
SCHEMBL983662 0.77 PTPN1 (0.45) PTPN1NCEH1LMNAALDH1A1RAB9A
SCHEMBL16236150 0.76 KMT2A (0.52) LMNASMN1; SMN2GAAMAPTNPSR1
SCHEMBL1836907 0.76 MYC (0.42) FABP4LMNAALDH1A1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108290820-B Method for recovering aromatic alcohol from melt polymerization and system for recovering same 沙特基础工业全球技术有限公司 2021-10-01 CN disclosed
EP-3038747-B1 TRANSESTERIFICATION OF AROMATIC ALCOHOLS USING A HETEROGENEOUS CATALYST SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-04-08 EP disclosed
EP-3545018-B1 SYNTHESIS OF A PHOSPHOROUS CONTAINING MONOMER AND THE INCORPORATION IN POLYCARBONATE BY INTERFACIAL POLYMERIZATION THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-02-19 EP disclosed
US-20200048410-A1 SYNTHESIS OF A PHOSPHOROUS CONTAINING MONOMER AND THE INCORPORATION IN POLYCARBONATE BY INTERFACIAL POLYMERIZATION THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-02-13 US disclosed
EP-3545018-A1 SYNTHESIS OF A PHOSPHOROUS CONTAINING MONOMER AND THE INCORPORATION IN POLYCARBONATE BY INTERFACIAL POLYMERIZATION THEREOF SABIC Global Technologies B.V. (NL) 2019-10-02 EP disclosed
EP-3383835-B1 A METHOD FOR RECOVERING AN AROMATIC ALCOHOL FROM A MELT POLYMERIZATION, AND A SYSTEM FOR RECOVERING THE SAME SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-07-24 EP disclosed
WO-2019048986-A1 METHOD FOR PRODUCING A POLYCARBONATE ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-03-14 WO disclosed
EP-2711353-B1 Process for the continuous manufacture of aryl alkyl carbonate and diaryl carbonate using vapor recompression SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-10-31 EP disclosed
WO-2018191612-A1 SYNTHESIS OF A PHOSPHOROUS CONTAINING MONOMER AND THE INCORPORATION IN POLYCARBONATE BY INTERFACIAL POLYMERIZATION THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-10-18 WO disclosed
EP-3383835-A1 A METHOD FOR RECOVERING AN AROMATIC ALCOHOL FROM A MELT POLYMERIZATION, AND A SYSTEM FOR RECOVERING THE SAME SABIC Global Technologies B.V. (NL) 2018-10-10 EP disclosed
WO-2014045086-A1 PROCESS FOR THE CONTINUOUS MANUFACTURE OF ARYL ALKYL CARBONATE AND/OR DIARYL CARBONATE USING VAPOR RECOMPRESSION SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-03-27 WO disclosed
EP-2711353-A1 Process for the continuous manufacture of aryl alkyl carbonate and diaryl carbonate using vapor recompression SABIC Innovative Plastics IP B.V. (NL) 2014-03-26 EP disclosed
US-20140081039-A1 PROCESS FOR THE CONTINUOUS MANUFACTURE OF ARYL ALKYL CARBONATE AND/OR DIARYL CARBONATE USING VAPOR RECOMPRESSION SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-03-20 US disclosed
US-8039659-B2 Processes for preparing diaryl and/or alkylaryl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG (DE) 2011-10-18 US disclosed
US-20110206568-A1 PROCESS FOR THE PREPARATION OF DIARYL CARBONATES OR ARYLALKYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2011-08-25 US disclosed
US-8003817-B2 Process for the preparation of diaryl carbonates or arylalkyl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG (DE) 2011-08-23 US disclosed
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2009-03-19 US disclosed
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates BAYER MATERIALSCIENCE AG (DE) 2008-11-27 US disclosed
US-7091302-B2 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG (DE) 2006-08-15 US disclosed
US-20050239995-A1 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates HDHD5, ALKBH3, AHR PTPN1 4280/4885FABP4 2464/4885NCEH1 1949/4885
US-20140081039-A1 PROCESS FOR THE CONTINUOUS MANUFACTURE OF ARYL ALKYL CARBONATE AND/OR DIARYL CARBONATE USING VAPOR RECOMPRESSION DOT1L, ALKBH5, AGL PTPN1 2961/4885FABP4 780/4885NCEH1 3541/4885
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES DHCR7, ADH1C, AKR1C4 PTPN1 4611/4885FABP4 746/4885NCEH1 649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.