SCHEMBL2355700

SCHEMBL2355700

c1cnc(C2CCCCC2)c(C2CCCCC2)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.40
KDM4E B2RXH2 2/20 0.38
GAA P10253 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
JAK2 O60674 3/20 0.36
JAK1 P23458 3/20 0.36
TYK2 P29597 3/20 0.36
JAK3 P52333 3/20 0.36
OPRL1 P41146 2/20 0.35
TDO2 P48775 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
GLA P06280 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
HIF1A Q16665 1/20 0.34
KMO O15229 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HRH2 P25021 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6645065 0.85 OPRL1 (0.36) GAAOPRL1SMN1; SMN2NOTUM
SCHEMBL11679373 0.84 OPRL1 (0.37) CYP11B2KDM4EGAANISCHL3MBTL1
SCHEMBL7937826 0.84 NISCH (0.36) CYP11B2KDM4EGAANISCHL3MBTL1
SCHEMBL548100 0.84 OPRL1 (0.45) CYP11B2KDM4EL3MBTL1JAK2JAK1
SCHEMBL28563124 0.84 TDO2 (0.37) CYP11B2KDM4EGAANISCHJAK2
SCHEMBL11680081 0.84 CYP11B2 (0.34) CYP11B2KDM4EGAANISCHL3MBTL1
SCHEMBL1304488 0.80 OPRL1 (0.35) CYP11B2OPRL1TDO2
SCHEMBL11227288 0.80 CYP11B2 (0.31) CYP11B2KDM4EL3MBTL1TDP1SMN1; SMN2
SCHEMBL25053737 0.75 CYP11B2 (0.44) CYP11B2KDM4EGAAL3MBTL1TDP1
SCHEMBL1253356 0.75 CYP11B2 (0.44) CYP11B2KDM4EGAAL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106009664-B Compositions, composites prepared therefrom, and films and electronic devices including the same 三星电子株式会社 2020-02-04 CN claimed
US-5720897-A A COMPLEXES AS ANTIDEPOSITING AGENT, PRECIPITATION INHIBITOR UNIVERSITY OF FLORIDA (US) 1998-02-24 US claimed
CN-112469768-B Polymerization condition setting method and method for producing optical material 三井化学株式会社 2023-04-28 CN disclosed
CN-115151687-A Core-sheath composite fiber for artificial hair, head ornament product comprising same, and method for producing same 株式会社钟化 2022-10-04 CN disclosed
CN-109021236-B Polyimide or poly (amide-imide) film, display device including the same, and method of preparing the same 三星电子株式会社 2022-09-30 CN disclosed
CN-114518614-A Laminated film, and display device including the same 三星电子株式会社 2022-05-20 CN disclosed
CN-109239816-B Laminated film, and display device including the same 三星电子株式会社 2022-02-25 CN disclosed
CN-106967296-B Compositions for preparing organic-inorganic hybrid poly (amide-imide) copolymers, articles made therefrom, and display devices 三星电子株式会社 2021-05-25 CN disclosed
CN-106928706-B Compositions for making polyimide or poly (imide-amide) copolymer articles, and display devices including the same 三星电子株式会社 2021-03-16 CN disclosed
CN-105739150-B Window for display device and display device including the same 三星电子株式会社 2020-05-12 CN disclosed
CN-111019175-A Laminated film and display device including the same 三星电子株式会社 2020-04-17 CN disclosed
US-8378122-B2 Process for the preparation of chymase modulators JANSSEN PHARMACEUTICA NV. (BE) 2013-02-19 US disclosed
US-20120309986-A1 PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS ANZALONE LUIGI (US) 2012-12-06 US disclosed
US-8263785-B2 Process for the preparation of chymase modulators JANSSEN PHARMACEUTICA N.V. (BE) 2012-09-11 US disclosed
US-20110192788-A1 METHOD FOR PRODUCING POROUS THERMOSETTING RESIN SHEET, POROUS THERMOSETTING RESIN SHEET AND COMPOSITE SEMIPERMEABLE MEMBRANE USING SAME NITTO DENKO CORPORATION (JP) 2011-08-11 US disclosed
US-20100145075-A1 PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2010-06-10 US disclosed
WO-2010051372-A1 PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2010-05-06 WO disclosed
US-5720897-A A COMPLEXES AS ANTIDEPOSITING AGENT, PRECIPITATION INHIBITOR UNIVERSITY OF FLORIDA (US) 1998-02-24 US disclosed
US-5369183-A Thermoplastic resin and acrylic ester compound containing dicyclopentadiene type alicyclic ring SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1994-11-29 US disclosed
EP-0423998-A2 Composite and moulded articles therefrom SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1991-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309986-A1 PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS CMA1, SERPINB1, CPA3 CYP11B2 1527/4885KDM4E 2815/4885GAA 174/4885
US-20100145075-A1 PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS CMA1, SERPINB1, CPA3 CYP11B2 1527/4885KDM4E 2815/4885GAA 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.