Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.66 |
| ▸ | P2RY14 | Q15391 | 8/20 | 0.64 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14152110 | 0.87 | HSD17B1 (0.71) | PTGS2HSD17B1HSD17B2MIFCA12 | |
| SCHEMBL23528100 | 0.87 | P2RY14 (0.62) | PTGS2P2RY14HSD17B1HSD17B2OPRD1 | |
| SCHEMBL12420376 | 0.85 | PTGS2 (0.65) | PTGS2P2RY14S1PR1OPRD1SIGMAR1 | |
| SCHEMBL18031616 | 0.83 | HSD17B1 (0.75) | PTGS2P2RY14HSD17B1HSD17B2NOTUM | |
| SCHEMBL23557634 | 0.83 | HSD17B1 (0.71) | PTGS2P2RY14HSD17B1HSD17B2NOTUM | |
| SCHEMBL182551 | 0.83 | P2RY14 (0.78) | PTGS2P2RY14S1PR1OPRD1SIGMAR1 | |
| SCHEMBL18031110 | 0.83 | HSD17B1 (0.71) | PTGS2P2RY14HSD17B1HSD17B2NOTUM | |
| SCHEMBL23557718 | 0.83 | PTGS2 (0.63) | PTGS2HSD17B1HSD17B2MIFCA12 | |
| SCHEMBL18031100 | 0.83 | PTGS2 (0.63) | PTGS2HSD17B1HSD17B2MIFCA12 | |
| SCHEMBL18031102 | 0.82 | CA1 (0.56) | PTGS2P2RY14HSD17B1HSD17B2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188785-A1 | SULFAMATE DERIVATIVES OF 4-(1-PHENYL-1H-[1,2,3]TRIAZOL-4-YL)-PHENOL, DERIVATIVES OF 4-(1-PHENYL-1H-[1,2,3]TRIAZOL-4-YL)-PHENOL, THEIR MEDICAL USE AND THE METHOD OF OBTAINING 4-(1-PHENYL-1H-[1,2,3]TRIAZOL-4-YL)-PHENYL SULFAMATE DERIVATIVES | POLITECHNIKA GDANSKA (PL) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188785-A1 | SULFAMATE DERIVATIVES OF 4-(1-PHENYL-1H-[1,2,3]TRIAZOL-4-YL)-PHENOL, DERIVATIVES OF 4-(1-PHENYL-1H-[1,2,3]TRIAZOL-4-YL)-PHENOL, THEIR MEDICAL USE AND THE METHOD OF OBTAINING 4-(1-PHENYL-1H-[1,2,3]TRIAZOL-4-YL)-PHENYL SULFAMATE DERIVATIVES | SULT1E1, SULT2A1, SULT1A1 | PTGS2 238/4885P2RY14 124/4885HSD17B1 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.