SCHEMBL2355854

SCHEMBL2355854

CCC(C)(CC)OC(=O)C1=CCC(=O)C=C1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
NFKB1 P19838 2/20 0.33
NFKB2 Q00653 2/20 0.33
RELA Q04206 2/20 0.33
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11229915 0.86 NFKB1 (0.39) NFKB1NFKB2RELA
SCHEMBL47924 0.78 CA12 (0.42) CYP1A2NFKB1NFKB2RELA
SCHEMBL48012 0.75 LMNA (0.37) NFKB1NFKB2RELA
SCHEMBL47935 0.75 ALDH1A1 (0.43)
SCHEMBL7035636 0.74 LMNA (0.36) NFKB1NFKB2RELA
SCHEMBL3110549 0.74 SERPINE1 (0.37)
SCHEMBL3205528 0.73 ALDH1A1 (0.32)
SCHEMBL1682242 0.73 CA12 (0.43) CYP1A2CYP2C19
SCHEMBL1435298 0.72 ALDH1A1 (0.46) NFKB1
SCHEMBL659382 0.71 ALDH1A1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003119-B2 Composition for pharmaceutical or dietetic use for combating hair loss GIULIANI S.P.A. (IT) 2011-08-23 US disclosed
US-7276538-B2 Composition and a method for treating hair loss GIULIANI S.P.A. (IT) 2007-10-02 US disclosed
EP-1469843-B1 COMPOSITION FOR PHARMACEUTICAL OR DIETETIC USE FOR COMBATING HAIR LOSS GIULIANI SPA (IT) 2007-07-04 EP disclosed
US-20060222620-A1 Composition for pharmaceutical or dietetic use for combating hair loss GIULIANI S.P.A. (IT) 2006-10-05 US disclosed
US-20050147577-A1 Composition for pharmaceutical or dietetic use for combating hair loss GIULIANI S.P.A. (IT) 2005-07-07 US disclosed
EP-1469843-A1 COMPOSITION FOR PHARMACEUTICAL OR DIETETIC USE FOR COMBATING HAIR LOSS GIULIANI S.p.A. (IT) 2004-10-27 EP disclosed
WO-2003063851-A1 COMPOSITION FOR PHARMACEUTICAL OR DIETETIC USE FOR COMBATING HAIR LOSS GIULIANI S.P.A. (IT) 2003-08-07 WO disclosed