Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768081 | 0.79 | — | — | |
| SCHEMBL1810305 | 0.79 | CYP2C19 (0.38) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3253959 | 0.77 | CYP2C19 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6802128 | 0.76 | GNAI3 (0.32) | SMN1; SMN2 | |
| SCHEMBL10501307 | 0.76 | ALDH1A1 (0.35) | POLBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL578419 | 0.76 | JAK2 (0.31) | JAK2JAK1JAK3SMN1; SMN2 | |
| SCHEMBL9370283 | 0.75 | CYP2C19 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1768062 | 0.74 | — | — | |
| Urea SCHEMBL1835314 | 0.72 | ALOX5 (0.46) | SMN1; SMN2ALOX5 | |
| Hydrochloric Acid SCHEMBL27793068 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127328-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |