Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.65 |
| ▸ | CA2 | P00918 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11663639 | 0.85 | CA1 (0.49) | CA1CA2KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL7703075 | 0.80 | PLA2G2A (0.73) | CA1CA2KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL27839378 | 0.79 | CA1 (0.41) | CA1CA2KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL9311 | 0.79 | CA1 (0.56) | CA1CA2KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL4261482 | 0.79 | CA1 (1.00) | CA1CA2KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL2318320 | 0.79 | CA1 (0.65) | CA1CA2KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL27522930 | 0.79 | CA1 (0.65) | CA1CA2KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL11212 | 0.79 | KDM4E (0.68) | CA1CA2KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL8665 | 0.78 | CA1 (0.59) | CA1CA2KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL693914 | 0.78 | KMT2A (0.69) | CA1CA2KDM4ECYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414743-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2019-09-17 | — | — | US | disclosed |
| US-9556382-B2 | Polymerisable mixtures and the use thereof in liquid crystal displays | MERCK PATENT GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-20160159763-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-9279082-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2016-03-08 | — | — | US | disclosed |
| CN-103025773-B | Polymerizable mixture and use thereof in liquid crystal displays | MERCK PATENT GMBH | 2015-07-15 | — | — | CN | disclosed |
| EP-2665798-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-10-08 | — | — | EP | disclosed |
| CN-102197109-B | Liquid crystal display | MERCK PATENT GMBH | 2014-05-14 | — | — | CN | disclosed |
| EP-2665798-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2013-11-27 | — | — | EP | disclosed |
| US-8592007-B2 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2013-11-26 | — | — | US | disclosed |
| US-20130308081-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| US-20130114010-A1 | POLYMERISABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| CN-103025773-A | Polymerizable mixture and use thereof in liquid crystal displays | MERCK PATENT GMBH | 2013-04-03 | — | — | CN | disclosed |
| WO-2012097858-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2012-07-26 | — | — | WO | disclosed |
| CN-102197109-A | Liquid crystal display | MERCK PATENT GMBH | 2011-09-21 | — | — | CN | disclosed |
| US-20110205482-A1 | LIQUID-CRYSTAL DISPLAY | MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) | 2011-08-25 | — | — | US | disclosed |
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | UNIVERSITY OF MISSISSIPPI | 2009-07-30 | — | — | US | disclosed |
| US-7468445-B2 | Antigiardial agents and use thereof | UNIVERSITY OF MISSISSIPPI (US) | 2008-12-23 | — | — | US | disclosed |
| US-20060106091-A1 | Antigiardial agents and use thereof | THE UNIVERSITY OF MISSISSIPPI | 2006-05-18 | — | — | US | disclosed |
| WO-2004014886-A1 | ANTIGIARDIAL AGENTS AND USE THEREOF | UNIVERSITY OF MISSISSIPPI (US) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106091-A1 | Antigiardial agents and use thereof | GPER1, ENPP2, ALPI | CA1 1070/4885CA2 341/4885KDM4E 2433/4885 |
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | ENPP2, GPER1, ALPI | CA1 1098/4885CA2 431/4885KDM4E 2954/4885 |
| US-10414743-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, LPXN, ACP3 | CA1 497/4885CA2 1451/4885KDM4E 2990/4885 |
| US-20110205482-A1 | LIQUID-CRYSTAL DISPLAY | VCL, LPXN, LCP1 | CA1 799/4885CA2 1574/4885KDM4E 3159/4885 |
| US-20160159763-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, LPXN, LCP1 | CA1 518/4885CA2 1431/4885KDM4E 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.