SCHEMBL11212

SCHEMBL11212

Cc1oc2ccccc2c(=O)c1-c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.68
ALDH1A1 P00352 4/20 0.68
CA1 P00915 5/20 0.65
CA2 P00918 5/20 0.65
CYP2C9 P11712 2/20 0.64
CYP1A2 P05177 1/20 0.64
CYP2C19 P33261 1/20 0.64
MAPT P10636 3/20 0.58
PKM P14618 2/20 0.55
GAA P10253 2/20 0.55
POLB P06746 1/20 0.55
RECQL P46063 1/20 0.55
CYP3A4 P08684 3/20 0.53
HPGD P15428 3/20 0.53
MAOA P21397 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
HSD17B10 Q99714 2/20 0.53
GLA P06280 1/20 0.53
PGAM1 P18669 1/20 0.53
CASP1 P29466 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8364 0.88 MAPK14 (0.59) KDM4EALDH1A1CA1CA2CYP2C9
SCHEMBL31217592 0.87 CA1 (0.68) KDM4EALDH1A1CA1CA2CYP2C9
SCHEMBL12695627 0.85 MAPT (0.49) KDM4EALDH1A1CA1CA2CYP2C9
SCHEMBL8646 0.83 GABRP (0.56) KDM4EALDH1A1CA1CA2CYP2C9
SCHEMBL8608 0.82 KDM4E (0.59) KDM4EALDH1A1CA1CA2CYP2C9
SCHEMBL3268493 0.81 CA1 (0.59) KDM4EALDH1A1CA1CA2CYP2C9
SCHEMBL5266910 0.81 ALDH1A1 (1.00) KDM4EALDH1A1CYP2C9CYP1A2CYP2C19
SCHEMBL8860 0.81 KDM4E (0.58) KDM4EALDH1A1CA1CA2CYP2C9
SCHEMBL7703075 0.80 PLA2G2A (0.73) KDM4EALDH1A1CA1CA2MAPT
SCHEMBL31276071 0.79 ALDH1A1 (0.52) KDM4EALDH1A1CA1CA2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040408-A Colorimetric-near infrared dual-detection fluorescent probe for hypochlorous acid detection and preparation method and application thereof 镇江江南化工有限公司 2025-05-27 CN claimed
CN-110922375-A Fluorescent probe for detecting viscosity and preparation method and application thereof 济南大学 2020-03-27 CN claimed
CN-120040408-A Colorimetric-near infrared dual-detection fluorescent probe for hypochlorous acid detection and preparation method and application thereof 镇江江南化工有限公司 2025-05-27 CN disclosed
CN-119432884-A Polygonatum cyrtonema PcOMT gene and application thereof in promotion of high isoflavone synthesis and methylation 浙江农林大学 2025-02-14 CN disclosed
US-20240360095-A1 NOVEL KINASE MODULATORS RHIZEN PHARMACEUTICALS AG (CH) 2024-10-31 US disclosed
CN-114657160-B Glycosyltransferase mutant and application thereof 浙江康恩贝制药股份有限公司 2024-04-05 CN disclosed
US-11858907-B2 Kinase modulators RHIZEN PHARMACEUTICALS AG (CH) 2024-01-02 US disclosed
CN-117214367-A Method for measuring chemical components of rabdosia rubescens by using UPLC-Q-TOF-MS 杭州胡庆余堂药业有限公司 2023-12-12 CN disclosed
CN-112915096-B Pharmaceutical application of echinocystic acid-28-O-beta-D-glucoside 天津中医药大学 2022-12-20 CN disclosed
CN-114657160-A Glycosyl transferase mutant and application thereof 浙江康恩贝制药股份有限公司 2022-06-24 CN disclosed
CN-112716936-B Preparation method of puerarin nanoparticles 江西中医药大学 2022-03-18 CN disclosed
CN-1684950-A Preparation of isoflavones DSM IP ASSETS BV (NL) 2005-10-19 CN disclosed
EP-1523478-A2 MANUFACTURE OF ISOFLAVONES DSM IP Assets B.V. (NL) 2005-04-20 EP disclosed
WO-2004009576-A2 MANUFACTURE OF ISOFLAVONES DSM IP ASSETS B.V. (NL) 2004-01-29 WO disclosed
CN-1077767-C Method and compositions for stimulating vesicular-arbuscular mycorrhizal fungi UNIV MICHIGAN STATE (US) 2002-01-16 CN disclosed
US-6087385-A AN ANTIPROLIFERATIVE, ANTIINFLAMMATORY AND ANTIINFECTIVE AGENTS FOR THE TREATMENT OF CERTAIN ENDOCRINE DISEASES LIKE DIABETES, PROSTATE CANCER, BREAST CANCER, PSORIASIS, ACNE, CERTAIN CARDIOVASCULAR DISORDERS INCLUDING HYPERTENSION UNIVERSITY OF MISSISSIPPI (US) 2000-07-11 US disclosed
US-6028088-A USEFUL AS ANTIPROLIFERATIVE, ANTIINFLAMMATORY AND ANTIINFECTIVE AGENTS; FOR TREATMENT OF CERTAIN ENDOCRINE DISEASES INCLUDING DIABETES, CERTAIN MALIGNANT AND NON-MALIGNANT PROLIFERATIVE DISEASES INCLUDING PROSTATE CANCER THE UNIVERSITY OF MISSISSIPPI (US) 2000-02-22 US disclosed
CN-1040458-C Method for stimulating plant growth in the presence of vesicular arbuscular mycorrhizal fungi UNIV MICHIGAN STATE (US) 1998-10-28 CN disclosed
CN-1186599-A Method and compositions for stimulating vesicular-arbuscular mycorrhizal fungi UNIV MICHIGAN STATE (US) 1998-07-08 CN disclosed
CN-1052329-A Methods and compositions for stimulating vesicular-arbuscular mycorrhizal fungi UNIV MICHIGAN STATE (US) 1991-06-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360095-A1 NOVEL KINASE MODULATORS PRKCA, PRKCH, PRKCB KDM4E 2418/4885ALDH1A1 4305/4885CA1 4615/4885
US-11858907-B2 Kinase modulators RPS6KA1, RPS6KA2, PRKAR2A KDM4E 3690/4885ALDH1A1 3748/4885CA1 4543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.