Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23567447 | 0.81 | RAB9A (0.43) | NOTUMACHEGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL23566934 | 0.77 | NOTUM (0.46) | NOTUMPGRSMN1; SMN2 | |
| SCHEMBL23567063 | 0.76 | MAPK14 (0.50) | NOTUMACHEPTGS2 | |
| SCHEMBL10166445 | 0.76 | CHRM2 (0.38) | ACHEESR2LMNASMN1; SMN2PTGS2 | |
| SCHEMBL14149760 | 0.75 | NPC1 (0.48) | NOTUMACHEGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL9955412 | 0.71 | NOTUM (0.47) | NOTUMACHETAAR1ESR2MGAM | |
| SCHEMBL19170354 | 0.70 | TAAR1 (0.52) | ACHETAAR1ESR2TNKS2MGAM | |
| SCHEMBL198702 | 0.70 | TAAR1 (0.68) | NOTUMACHETAAR1ESR2 | |
| SCHEMBL18970517 | 0.68 | TAAR1 (0.50) | ACHETAAR1ESR2TNKS2MGAM | |
| SCHEMBL18970556 | 0.68 | TAAR1 (0.50) | ACHETAAR1ESR2TNKS2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210186927-A1 | COMBINATION PRODUCT FOR THE INDUCTION AND/OR MAINTENANCE OF GENERAL ANESTHESIA | TERRAN BIOSCIENCES, INC. | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210186927-A1 | COMBINATION PRODUCT FOR THE INDUCTION AND/OR MAINTENANCE OF GENERAL ANESTHESIA | OPRK1, OPRD1, GABRD | NOTUM 4430/4885ACHE 438/4885TAAR1 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.