Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22606460 | 0.91 | CHRNB2 (0.34) | — | |
| SCHEMBL19942536 | 0.74 | CHRNB2 (0.36) | — | |
| SCHEMBL24782508 | 0.73 | CHRNB2 (0.34) | — | |
| SCHEMBL16146012 | 0.71 | EPHX1 (0.41) | — | |
| SCHEMBL10169316 | 0.70 | GRM4 (0.39) | — | |
| SCHEMBL19942385 | 0.69 | ALDH1A1 (0.37) | POLB | |
| SCHEMBL24782517 | 0.68 | CHRNB2 (0.32) | — | |
| SCHEMBL11982366 | 0.67 | MEN1 (0.43) | POLB | |
| SCHEMBL7909626 | 0.67 | PKM (0.36) | — | |
| SCHEMBL24754202 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332477-B2 | Nitrogen containing heterocycle substituted benzoxazine oxazolidinone compound and preparation method and use thereof | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2022-05-17 | — | — | US | disclosed |
| US-20210188871-A1 | NITROGEN CONTAINING HETEROCYCLE SUBSTITUTED BENZOXAZINE OXAZOLIDINONE COMPOUND AND PREPARATION METHOD AND USE THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188871-A1 | NITROGEN CONTAINING HETEROCYCLE SUBSTITUTED BENZOXAZINE OXAZOLIDINONE COMPOUND AND PREPARATION METHOD AND USE THEREOF | XDH, NOX5, TBC1D15 | POLB 1864/4885 |
| US-11332477-B2 | Nitrogen containing heterocycle substituted benzoxazine oxazolidinone compound and preparation method and use thereof | XDH, NOX5, TBC1D15 | POLB 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.