Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771085 | 0.79 | MEN1 (0.41) | NPSR1GAAALDH1A1MAPTKMT2A | |
| SCHEMBL14850518 | 0.79 | MKNK1 (0.47) | L3MBTL1LMNANPSR1TDP1KDM4E | |
| SCHEMBL4826971 | 0.79 | PTGS2 (0.51) | L3MBTL1LMNANPSR1KDM4EALDH1A1 | |
| SCHEMBL544517 | 0.78 | MKNK1 (0.59) | L3MBTL1LMNANPSR1TDP1KDM4E | |
| SCHEMBL170710 | 0.76 | TDO2 (0.61) | L3MBTL1LMNANPSR1TDP1KDM4E | |
| SCHEMBL9168467 | 0.74 | LMNA (0.50) | L3MBTL1LMNANPSR1TDP1KDM4E | |
| SCHEMBL12788076 | 0.74 | LMNA (0.50) | L3MBTL1LMNANPSR1TDP1KDM4E | |
| SCHEMBL3038829 | 0.74 | KDM4E (0.50) | L3MBTL1LMNANPSR1TDP1KDM4E | |
| SCHEMBL19026193 | 0.74 | NPSR1 (0.50) | L3MBTL1LMNANPSR1TDP1KDM4E | |
| SCHEMBL367037 | 0.74 | TDO2 (0.59) | L3MBTL1LMNANPSR1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116734-A1 | FUSED PYRROLIDINE COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF RESPIRATORY VIRAL INFECTIONS | SHANGHAI MICURX PHARMACEUTICAL CO., LTD. (CN) | 2023-06-29 | — | — | WO | disclosed |
| US-11659766-B2 | Organic semiconductor material for electron transport | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2023-05-23 | — | — | US | disclosed |
| US-11659766-B2 | Organic semiconductor material for electron transport | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2023-05-23 | — | — | US | disclosed |
| US-20200345804-A1 | NOVEL AGENTS TARGETING INHIBITOR OF APOPTOSIS PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-11-05 | — | — | US | disclosed |
| US-20190189933-A1 | ORGANIC SEMICONDUCTOR MATERIAL FOR ELECTRON TRANSPORT | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2019-06-20 | — | — | US | disclosed |
| US-20170136084-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2017-05-18 | — | — | US | disclosed |
| US-20170136084-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2017-05-18 | — | — | US | disclosed |
| US-9586991-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20160102119-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2016-04-14 | — | — | US | disclosed |
| US-9238675-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2016-01-19 | — | — | US | disclosed |
| US-7345081-B2 | Azabicyclo-octane inhibitors of IAP | GENENTECH, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| WO-2008014238-A2 | DIMERIC IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORPORATION (US) | 2008-01-31 | — | — | WO | disclosed |
| US-20070299052-A1 | Inhibitors of IAP | GENENTECH, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070299052-A1 | Inhibitors of IAP | GENENTECH, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| US-7244851-B2 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | GENENTECH, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244851-B2 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | GENENTECH, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| US-20070135477-A1 | Benzimidazole derivatives and their use as protein kinases inhibitors | ASTEX THERAPEUCTICS, LIMITED (US) | 2007-06-14 | — | — | US | disclosed |
| US-20070135477-A1 | Benzimidazole derivatives and their use as protein kinases inhibitors | ASTEX THERAPEUCTICS, LIMITED (US) | 2007-06-14 | — | — | US | disclosed |
| US-7160874-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-20070004677-A1 | Linear urea mimics antagonists of P2Y1 receptor useful in the treatment of thrombotic condition | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170136084-A1 | INHIBITORS OF IAP | BIRC5, XIAP, BIRC3 | L3MBTL1 336/4885LMNA 2547/4885NPSR1 4030/4885 |
| US-20070004677-A1 | Linear urea mimics antagonists of P2Y1 receptor useful in the treatment of thrombotic condition | P2RY1, P2RY11, UTS2R | L3MBTL1 3656/4885LMNA 3418/4885NPSR1 54/4885 |
| US-20070299052-A1 | Inhibitors of IAP | XIAP, BIRC5, BIRC3 | L3MBTL1 317/4885LMNA 1500/4885NPSR1 3542/4885 |
| US-20160102119-A1 | INHIBITORS OF IAP | BIRC5, XIAP, BIRC3 | L3MBTL1 336/4885LMNA 2547/4885NPSR1 4030/4885 |
| US-20200345804-A1 | NOVEL AGENTS TARGETING INHIBITOR OF APOPTOSIS PROTEINS | XIAP, BIRC2, BIRC5 | L3MBTL1 502/4885LMNA 1297/4885NPSR1 4867/4885 |
| US-20070135477-A1 | Benzimidazole derivatives and their use as protein kinases inhibitors | CDK1, AURKA, CDK2 | L3MBTL1 2624/4885LMNA 691/4885NPSR1 4868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.