Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.43 |
| ▸ | RBP4 | P02753 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355876 | 0.87 | FFAR4 (0.42) | RBP4TTRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2227841 | 0.85 | SLC6A2 (0.52) | RBP4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2227838 | 0.85 | SLC6A2 (0.52) | RBP4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2285047 | 0.85 | SLC6A2 (0.52) | RBP4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2227124 | 0.80 | MMP2 (0.44) | F2GRIN2BKDM4ETNFLMNA | |
| SCHEMBL2229023 | 0.80 | MMP2 (0.45) | F2GRIN2BKDM4ETNFLMNA | |
| SCHEMBL2790672 | 0.79 | FAAH (0.46) | F2FFAR1 | |
| SCHEMBL2793669 | 0.79 | FAAH (0.46) | F2FFAR1 | |
| SCHEMBL20744482 | 0.78 | CHRNB4 (0.52) | F2RBP4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20744463 | 0.78 | CHRNB4 (0.52) | F2RBP4GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |