Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389751 | 0.80 | ALDH1A1 (0.56) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL634085 | 0.75 | ALDH1A1 (0.79) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL11782254 | 0.71 | MMP2 (0.56) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL7765161 | 0.71 | ALDH1A1 (0.55) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL12386314 | 0.70 | GAA (0.53) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL15199346 | 0.70 | ALDH1A1 (0.57) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL2624207 | 0.70 | ALDH1A1 (0.63) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL7100203 | 0.70 | GAA (0.64) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL7049553 | 0.70 | GAA (0.64) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL187561 | 0.69 | GAA (0.70) | ALDH1A1GAASMN1; SMN2CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046684-B2 | Compound for selectively inhibiting kinase and use thereof | SHANGHAI ZHEYE BIOTECHNOLOGY LIMITED LIABILITY COMPANY (CN) | 2021-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046684-B2 | Compound for selectively inhibiting kinase and use thereof | FGFR4, FGFR1, FGFR3 | ALDH1A1 2511/4885GAA 1810/4885SMN1; SMN2 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.