Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579068 | 0.83 | CTSS (0.36) | CD38GPR119HCRTR2KDM4EALDH1A1 | |
| SCHEMBL23579069 | 0.83 | CTSS (0.36) | CD38GPR119HCRTR2KDM4EALDH1A1 | |
| SCHEMBL29959217 | 0.83 | CTSS (0.36) | CD38GPR119HCRTR2KDM4EALDH1A1 | |
| SCHEMBL23579067 | 0.83 | CTSS (0.36) | CD38GPR119HCRTR2KDM4EALDH1A1 | |
| SCHEMBL24969956 | 0.83 | CTSS (0.36) | CD38GPR119HCRTR2KDM4EALDH1A1 | |
| SCHEMBL25063680 | 0.81 | PIK3CA (0.45) | CD38KDM4EALDH1A1HPGDPIK3CA | |
| SCHEMBL28059124 | 0.74 | KDM4E (0.43) | GPR119KDM4EALDH1A1HPGD | |
| SCHEMBL28385258 | 0.72 | AOC3 (0.42) | CD38HCRTR2KDM4EALDH1A1HPGD | |
| SCHEMBL28059065 | 0.72 | ADRB1 (0.52) | KDM4EALDH1A1 | |
| SCHEMBL23593426 | 0.69 | KDM1A (0.45) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133809-A1 | INHIBITORS OF MUTANT FORMS OF EGFR | BLUEPRINT MEDICINES CORPORATION (US) | 2021-07-01 | — | — | WO | disclosed |