Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059065 | 0.84 | ADRB1 (0.52) | KDM4ELMNAACHEALDH1A1HSP90AA1 | |
| SCHEMBL12597157 | 0.74 | KDM4E (0.55) | KDM4ELMNAACHEPOLBSMN1; SMN2 | |
| SCHEMBL23592736 | 0.74 | CD38 (0.42) | KDM4EGPR119ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10504874 | 0.73 | KDM4E (0.53) | KDM4ELMNAACHEPOLBSMN1; SMN2 | |
| SCHEMBL27941842 | 0.72 | GBA1 (0.55) | MAPK8CDC7ACHEGBA1CCNT1 | |
| SCHEMBL30635502 | 0.72 | GBA1 (0.55) | MAPK8CDC7ACHEGBA1CCNT1 | |
| SCHEMBL28059059 | 0.72 | MAPK8 (0.47) | KDM4ECHRNA7KMT2AMAPK8CDC7 | |
| SCHEMBL7904079 | 0.72 | SORD (0.55) | KDM4ELMNAACHEGBA1ALDH1A1 | |
| SCHEMBL13806030 | 0.72 | SORD (0.55) | KDM4ELMNAPOLBALDH1A1HPGD | |
| SCHEMBL18228454 | 0.72 | SORD (0.55) | KDM4ELMNAACHEGBA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814052-B | Imidazopyridine derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-105814052-A | Imidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |