Sugi Predict

Sugi Predict / Compounds / SCHEMBL2359645

SCHEMBL2359645

SCHEMBL2359645

Nc1ccn(-c2cc(F)ccc2F)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ ALDH1A1 P00352 5/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ RXRA P19793 2/20 0.35
▸ GRIN1 Q05586 2/20 0.35
▸ GRIN2B Q13224 2/20 0.35
▸ BACE1 P56817 1/20 0.34
▸ ESR1 P03372 1/20 0.34
▸ HPGD P15428 2/20 0.33
▸ ALOX15 P16050 2/20 0.33
▸ TSHR P16473 2/20 0.33
▸ HSD17B10 Q99714 2/20 0.33
▸ CA3 P07451 1/20 0.32
▸ CA6 P23280 1/20 0.32
▸ CA5A P35218 1/20 0.32
▸ CA9 Q16790 1/20 0.32
▸ CA14 Q9ULX7 1/20 0.32
▸ CA5B Q9Y2D0 1/20 0.32
▸ HTR2C P28335 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29572188 1.00 L3MBTL1 (0.41) L3MBTL1ALDH1A1MEN1KMT2ARXRA
SCHEMBL29571818 0.86 ALDH1A1 (0.41) L3MBTL1ALDH1A1MEN1KMT2ABACE1
SCHEMBL2357923 0.86 ALDH1A1 (0.41) L3MBTL1ALDH1A1MEN1KMT2ABACE1
SCHEMBL15638709 0.81 ALDH1A1 (0.38) L3MBTL1ALDH1A1MEN1KMT2AHTR2C
SCHEMBL29572092 0.81 ALDH1A1 (0.38) L3MBTL1ALDH1A1MEN1KMT2AHTR2C
SCHEMBL20249708 0.79 CRHR1 (0.40) L3MBTL1ALDH1A1MEN1KMT2ARXRA
SCHEMBL27859366 0.79 L3MBTL1 (0.39) L3MBTL1ALDH1A1MEN1KMT2ABACE1
SCHEMBL29572416 0.78 MEN1 (0.49) L3MBTL1ALDH1A1MEN1KMT2AHPGD
SCHEMBL403403 0.78 MEN1 (0.49) L3MBTL1ALDH1A1MEN1KMT2AHPGD
Hydrochloric Acid SCHEMBL5958352 0.76 MEN1 (0.47) L3MBTL1ALDH1A1MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11548854-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2023-01-10 — — US disclosed
US-11548854-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2023-01-10 — — US disclosed
US-11332448-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2022-05-17 — — US disclosed
US-11332448-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2022-05-17 — — US disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 — — CN disclosed
CN-113243374-A Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2021-08-13 — — CN disclosed
CN-108477173-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2021-07-02 — — CN disclosed
US-10961201-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2021-03-30 — — US disclosed
US-10961201-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2021-03-30 — — US disclosed
US-20210053924-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2021-02-25 — — US disclosed
EP-2903440-B1 HETEROCYCLIC COMPOUNDS AS PEST CONTROLLING AGENTS BAYER CROPSCIENCE AG (DE) 2017-09-06 — — EP disclosed
CN-105101800-A Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG 2015-11-25 — — CN disclosed
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2015-08-27 — — US disclosed
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2015-08-27 — — US disclosed
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2015-08-27 — — US disclosed
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 — — EP disclosed
WO-2014053450-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-04-10 — — WO disclosed
US-20110230497-A1 BIOLOGICALLY ACTIVE AMIDES H. LUNDBECK A/S (DK) 2011-09-22 — — US disclosed
EP-2352730-A2 BIOLOGICALLY ACTIVE AMIDES H. Lundbeck A/S (DK) 2011-08-10 — — EP disclosed
WO-2010053861-A2 BIOLOGICALLY ACTIVE AMIDES H. LUNDBECK A/S (DK) 2010-05-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10961201-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS L3MBTL1 563/4885ALDH1A1 2740/4885MEN1 2069/4885
US-20110230497-A1 BIOLOGICALLY ACTIVE AMIDES NPY5R, NPY1R, NPY2R L3MBTL1 4398/4885ALDH1A1 3024/4885MEN1 2360/4885
US-11548854-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS L3MBTL1 563/4885ALDH1A1 2740/4885MEN1 2069/4885
US-20210053924-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS L3MBTL1 563/4885ALDH1A1 2740/4885MEN1 2069/4885
US-11332448-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS L3MBTL1 563/4885ALDH1A1 2740/4885MEN1 2069/4885
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS L3MBTL1 563/4885ALDH1A1 2740/4885MEN1 2069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.