Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.67 |
| ▸ | ACHE | P22303 | 6/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305457 | 0.83 | HRH3 (0.67) | HRH3ACHEPARP1ALDH1A1HTR7 | |
| SCHEMBL21088453 | 0.81 | DRD2 (0.50) | ACHEDRD2DRD4DRD3BACE1 | |
| SCHEMBL470384 | 0.80 | HRH3 (0.59) | HRH3ALDH1A1 | |
| SCHEMBL3694234 | 0.80 | HRH3 (0.65) | HRH3ALDH1A1 | |
| SCHEMBL349216 | 0.79 | ALDH1A1 (0.62) | HRH3ALDH1A1 | |
| SCHEMBL211265 | 0.79 | LMNA (0.61) | HRH3ALDH1A1 | |
| SCHEMBL14032650 | 0.79 | SIGMAR1 (0.57) | HRH3ACHEDRD2 | |
| SCHEMBL156202 | 0.79 | HRH3 (0.76) | HRH3ACHEALDH1A1BACE1 | |
| SCHEMBL8275450 | 0.79 | HRH3 (0.76) | HRH3ACHEALDH1A1BACE1 | |
| SCHEMBL3682326 | 0.79 | HRH3 (0.69) | HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603127-A | Novel chalcone derivative containing nitrogen heterocycle, and preparation method and application thereof | 新疆医科大学 | 2024-02-27 | — | — | CN | disclosed |
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |