Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.53 |
| ▸ | WNT3A | P56704 | 1/20 | 0.50 |
| ▸ | SMO | Q99835 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ETV6 | P41212 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601156 | 0.88 | RET (0.56) | DPP4WNT3A | |
| SCHEMBL23601155 | 0.87 | DPP4 (0.63) | DPP4WNT3ASMOHPGDKDR | |
| SCHEMBL24721148 | 0.85 | PSEN1 (0.48) | WNT3ASMODGAT1KDRETV6 | |
| SCHEMBL23601169 | 0.84 | CKS1B (0.54) | DPP4WNT3ASMOHPGDSMN1; SMN2 | |
| SCHEMBL23601160 | 0.84 | GRM5 (0.50) | DPP4WNT3ASMOHPGDSMN1; SMN2 | |
| SCHEMBL23600946 | 0.81 | HRH3 (0.58) | SMOHPGDSMN1; SMN2CYP3A4HSD17B10 | |
| SCHEMBL15344195 | 0.80 | FYN (0.53) | CNR2 | |
| SCHEMBL23601153 | 0.80 | CNR2 (0.58) | SMN1; SMN2KDM4ECNR2 | |
| SCHEMBL12303103 | 0.77 | WNT3A (0.84) | WNT3A | |
| SCHEMBL23601163 | 0.77 | CNR2 (0.46) | DPP4DGAT1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |