Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | RET | P07949 | 4/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721285 | 0.84 | CNR2 (0.44) | CNR2RETPDE10AMAP4K4LRRK2 | |
| SCHEMBL24721010 | 0.84 | PSEN1 (0.44) | CNR2RETPDE10AMAP4K4HRH3 | |
| SCHEMBL23601153 | 0.83 | CNR2 (0.58) | CNR2TLR9TLR8TLR7ACHE | |
| SCHEMBL15344195 | 0.80 | FYN (0.53) | CNR2TLR9TLR8TLR7 | |
| SCHEMBL15034194 | 0.80 | HRH3 (0.55) | RETPDE10AMAP4K4HRH3 | |
| SCHEMBL23601164 | 0.79 | KCNH2 (0.57) | CNR2RETTLR9TLR8TLR7 | |
| SCHEMBL23601161 | 0.77 | DPP4 (0.53) | CNR2DGAT1DPP4 | |
| SCHEMBL23601170 | 0.76 | CNR2 (0.50) | CNR2RETACHEBACE1 | |
| SCHEMBL23601155 | 0.75 | DPP4 (0.63) | CNR2RETDPP4TLR8TLR7 | |
| SCHEMBL21588309 | 0.73 | MAP4K4 (0.48) | RETPDE10AMAP4K4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |