Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.50 |
| ▸ | RET | P07949 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721151 | 0.85 | CNR2 (0.47) | CNR2RETACVR1PIM1PIM3 | |
| SCHEMBL15344195 | 0.81 | FYN (0.53) | CNR2TNKS | |
| SCHEMBL23601153 | 0.81 | CNR2 (0.58) | CNR2ACHEBACE1KDM4E | |
| SCHEMBL14930368 | 0.81 | OGA (0.46) | CNR2RETPIM1PIM3PIM2 | |
| SCHEMBL23601164 | 0.77 | KCNH2 (0.57) | CNR2RETACVR1HDAC1 | |
| SCHEMBL23601163 | 0.76 | CNR2 (0.46) | CNR2RETACHEBACE1 | |
| SCHEMBL23601155 | 0.76 | DPP4 (0.63) | CNR2RET | |
| SCHEMBL23601551 | 0.75 | TBK1 (0.42) | KDM4EMAPT | |
| SCHEMBL19703397 | 0.74 | GRIN2D (0.46) | PIM1PIM3PIM2 | |
| SCHEMBL17642836 | 0.74 | ADRB1 (0.53) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |