Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.57 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15244897 | 0.90 | KCNH2 (0.56) | KCNH2CACNA1CASIC3HTR7HTR1A | |
| SCHEMBL15244966 | 0.90 | KCNH2 (0.56) | KCNH2CACNA1CASIC3HTR7HTR1A | |
| SCHEMBL23601153 | 0.87 | CNR2 (0.58) | TLR9TLR8TLR7CNR2 | |
| SCHEMBL15344195 | 0.84 | FYN (0.53) | HTR3ATLR9TLR8TLR7CNR2 | |
| SCHEMBL4582036 | 0.83 | ADRB1 (0.54) | ADRB1HTR7HTR1AHTR1DHTR2A | |
| SCHEMBL24721023 | 0.83 | TLR9 (0.53) | KCNH2CACNA1CASIC3HTR2CTLR9 | |
| SCHEMBL3442195 | 0.82 | GPR119 (0.59) | KCNH2CACNA1CASIC3ADRB1HTR7 | |
| SCHEMBL19497006 | 0.81 | NTRK1 (0.53) | KCNH2CACNA1CASIC3TLR9TLR8 | |
| SCHEMBL23601155 | 0.79 | DPP4 (0.63) | TLR8TLR7CNR2RET | |
| SCHEMBL23601163 | 0.79 | CNR2 (0.46) | TLR9TLR8TLR7CNR2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |