Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601197 | 0.83 | MAPT (0.43) | KMT2ACYP2C19MEN1 | |
| SCHEMBL23601722 | 0.81 | PDE5A (0.36) | — | |
| SCHEMBL23601069 | 0.81 | PDE5A (0.37) | — | |
| SCHEMBL23601707 | 0.80 | PDE5A (0.42) | — | |
| SCHEMBL23576768 | 0.77 | MAPK1 (0.35) | KMT2ACYP2C19MEN1POLBMMP14 | |
| SCHEMBL29909920 | 0.77 | MAPK1 (0.35) | KMT2ACYP2C19MEN1POLBMMP14 | |
| SCHEMBL23601308 | 0.77 | CSNK2A1 (0.39) | KMT2AMEN1POLBMAPK1 | |
| SCHEMBL23601391 | 0.77 | EGFR (0.46) | — | |
| SCHEMBL23601734 | 0.76 | PDE5A (0.34) | — | |
| SCHEMBL23601723 | 0.76 | PDE5A (0.36) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |