Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601069 | 0.88 | PDE5A (0.37) | PDE5ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL23601707 | 0.87 | PDE5A (0.42) | PDE5ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL23601391 | 0.84 | EGFR (0.46) | — | |
| SCHEMBL23601723 | 0.83 | PDE5A (0.36) | PDE5A | |
| SCHEMBL23601197 | 0.82 | MAPT (0.43) | — | |
| SCHEMBL23601308 | 0.82 | CSNK2A1 (0.39) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL23601519 | 0.81 | ABCG2 (0.46) | — | |
| SCHEMBL23601209 | 0.81 | SLC2A1 (0.35) | — | |
| SCHEMBL23601804 | 0.80 | CHEK1 (0.38) | PDE5ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL23601734 | 0.78 | PDE5A (0.34) | PDE5ACSNK2A1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |