Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601210 | 0.80 | PDE5A (0.36) | PDE5A | |
| SCHEMBL23601722 | 0.78 | PDE5A (0.36) | PDE5ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL23601069 | 0.78 | PDE5A (0.37) | PDE5ACSNK2A1CSNK2A2CSNK2BEGFR | |
| SCHEMBL23601707 | 0.77 | PDE5A (0.42) | PDE5ACSNK2A1CSNK2A2CSNK2BEGFR | |
| SCHEMBL23601209 | 0.76 | SLC2A1 (0.35) | — | |
| SCHEMBL23601230 | 0.76 | SIGMAR1 (0.41) | PDE5AEGFR | |
| SCHEMBL23601745 | 0.75 | ABCG2 (0.36) | PDE5AEGFR | |
| SCHEMBL23577984 | 0.74 | KMT2A (0.38) | PDE5ACSNK2A1PGRCSNK2A2CSNK2B | |
| SCHEMBL23601391 | 0.74 | EGFR (0.46) | EGFRCSF1R | |
| SCHEMBL29909873 | 0.74 | KMT2A (0.38) | PDE5ACSNK2A1PGRCSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |