Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601391 | 0.82 | EGFR (0.46) | — | |
| SCHEMBL23601197 | 0.82 | MAPT (0.43) | MEN1KMT2AFGFR1ALDH1A1MAPT | |
| SCHEMBL23601722 | 0.82 | PDE5A (0.36) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL23601069 | 0.81 | PDE5A (0.37) | CSNK2A1MAPTCSNK2A2CSNK2B | |
| SCHEMBL23601707 | 0.80 | PDE5A (0.42) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL23601557 | 0.78 | LMNA (0.40) | ALDH1A1HPGDHSD17B10ALOX15LMNA | |
| SCHEMBL23601519 | 0.77 | ABCG2 (0.46) | POLBMEN1KMT2AFGFR1ALDH1A1 | |
| SCHEMBL23601209 | 0.77 | SLC2A1 (0.35) | POLBMEN1KMT2AMAPK1 | |
| SCHEMBL23601723 | 0.77 | PDE5A (0.36) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL23577421 | 0.76 | CSNK2A1 (0.40) | CSNK2A1POLBMEN1KMT2AFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |