Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | XBP1 | P17861 | 3/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096257 | 0.91 | NPC1 (0.59) | NPC1MAPTHTTRAB9AXBP1 | |
| SCHEMBL16677163 | 0.91 | NPC1 (0.59) | NPC1MAPTHTTRAB9AXBP1 | |
| Inuchinenolide C SCHEMBL28264096 | 0.90 | NPC1 (0.51) | NPC1MAPTHTTRAB9AXBP1 | |
| SCHEMBL16639615 | 0.83 | NPC1 (0.62) | NPC1MAPTHTTRAB9AXBP1 | |
| SCHEMBL20376172 | 0.83 | NPC1 (0.57) | NPC1MAPTHTTRAB9AXBP1 | |
| SCHEMBL16641594 | 0.81 | NPC1 (0.60) | NPC1MAPTHTTRAB9AXBP1 | |
| SCHEMBL16644430 | 0.81 | NPC1 (0.59) | NPC1MAPTHTTRAB9AXBP1 | |
| SCHEMBL16639616 | 0.73 | NPC1 (0.50) | NPC1MAPTHTTRAB9AXBP1 | |
| Carabrolactone B SCHEMBL30040355 | 0.72 | MAPT (0.54) | NPC1MAPTHTTRAB9AXBP1 | |
| SCHEMBL23266629 | 0.70 | MAPT (0.67) | NPC1MAPTHTTRAB9AXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |
| WO-2024158867-A1 | A COMPOSITION FOR TREATING DERMATOLOGICAL CONDITIONS AND ITS METHOD OF MANUFACTURE | VIKTOR MICHAEL LLC (US) | 2024-08-02 | — | — | WO | disclosed |
| US-20210196676-A1 | TREATMENT OF VIRAL INFECTIONS AND VIRALLY ASSOCIATED LESIONS WITH SEQUITERPENE LACTONES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210196676-A1 | TREATMENT OF VIRAL INFECTIONS AND VIRALLY ASSOCIATED LESIONS WITH SEQUITERPENE LACTONES | CUTA, LTN1, HAVCR2 | NPC1 4732/4885MAPT 3547/4885HTT 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.