Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.59 |
| ▸ | XBP1 | P17861 | 3/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639615 | 0.92 | NPC1 (0.62) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL16641594 | 0.90 | NPC1 (0.60) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL16677163 | 0.89 | NPC1 (0.59) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL29096257 | 0.89 | NPC1 (0.59) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL16639616 | 0.82 | NPC1 (0.50) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL20376172 | 0.81 | NPC1 (0.57) | NPC1MAPTHTTRAB9AMAPK1 | |
| Chamissonolide SCHEMBL23601535 | 0.81 | NPC1 (0.52) | NPC1MAPTHTTRAB9AMAPK1 | |
| Ergolide SCHEMBL28262978 | 0.75 | PTGS2 (0.67) | NPC1MAPTHTTRAB9AMAPK1 | |
| Inuchinenolide C SCHEMBL28264096 | 0.75 | NPC1 (0.51) | NPC1MAPTHTTRAB9AMAPK1 | |
| Angustibalin SCHEMBL509228 | 0.74 | MAPT (1.00) | NPC1MAPTHTTRAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278948-B2 | Line leaf inula flower lactone A and methods for preparing and using the same for treating multiple sclerosis | SHANXI ZHENDONG PILOT BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2016-03-08 | — | — | US | disclosed |
| US-20150105458-A1 | LINE LEAF INULA FLOWER LACTONE A AND METHODS FOR PREPARING AND USING THE SAME FOR TREATING MULTIPLE SCLEROSIS | SHANXI ZHENDONG PILOT BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD. | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105458-A1 | LINE LEAF INULA FLOWER LACTONE A AND METHODS FOR PREPARING AND USING THE SAME FOR TREATING MULTIPLE SCLEROSIS | ACSL5, IL5, MSL1 | NPC1 2782/4885MAPT 2623/4885HTT 2249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.