Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.59 |
| ▸ | XBP1 | P17861 | 3/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16677163 | 1.00 | NPC1 (0.59) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL16639615 | 0.92 | NPC1 (0.62) | NPC1MAPTHTTRAB9AMAPK1 | |
| Chamissonolide SCHEMBL23601535 | 0.91 | NPC1 (0.52) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL16641594 | 0.90 | NPC1 (0.60) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL16644430 | 0.89 | NPC1 (0.59) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL20376172 | 0.89 | NPC1 (0.57) | NPC1MAPTHTTRAB9AMAPK1 | |
| Inuchinenolide C SCHEMBL28264096 | 0.84 | NPC1 (0.51) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL16639616 | 0.82 | NPC1 (0.50) | NPC1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL20953522 | 0.76 | NPC1 (0.47) | NPC1MAPTHTTRAB9AMAPK1 | |
| Ergolide SCHEMBL28262978 | 0.75 | PTGS2 (0.67) | NPC1MAPTHTTRAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739298-A1 | ACTIVATORS OF THE XC- SYSTEM AND/OR GPX-4 FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2026-05-13 | — | — | EP | claimed |
| WO-2025012137-A1 | ACTIVATORS OF THE XC- SYSTEM AND/OR GPX-4 FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2025-01-16 | — | — | WO | claimed |
| WO-2025012667-A1 | ACTIVATORS OF THE XC-SYSTEM AND/OR GPX-4 FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION. | SORBONNE UNIVERSITE (FR) | 2025-01-16 | — | — | WO | claimed |
| EP-4739297-A1 | MODULATORS OF LYPOXYGENASES FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2026-05-13 | — | — | EP | disclosed |
| EP-4739298-A1 | ACTIVATORS OF THE XC- SYSTEM AND/OR GPX-4 FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2026-05-13 | — | — | EP | disclosed |
| EP-4739300-A1 | MODULATORS OF IRON METABOLISM FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025012154-A1 | MODULATORS OF IRON METABOLISM FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2025-01-16 | — | — | WO | disclosed |
| WO-2025012668-A1 | MODULATORS OF IRON METABOLISM FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2025-01-16 | — | — | WO | disclosed |
| WO-2025012152-A1 | MODULATORS OF LYPOXYGENASES FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2025-01-16 | — | — | WO | disclosed |
| WO-2025012137-A1 | ACTIVATORS OF THE XC- SYSTEM AND/OR GPX-4 FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2025-01-16 | — | — | WO | disclosed |
| WO-2025012667-A1 | ACTIVATORS OF THE XC-SYSTEM AND/OR GPX-4 FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION. | SORBONNE UNIVERSITE (FR) | 2025-01-16 | — | — | WO | disclosed |
| CN-118615278-A | Application of inula flower lactone in preparation of medicine for treating colonitis | 广州中医药大学(广州中医药研究院) | 2024-09-10 | — | — | CN | disclosed |
| CN-118615278-A | Application of inula flower lactone in preparation of medicine for treating colonitis | 广州中医药大学(广州中医药研究院) | 2024-09-10 | — | — | CN | disclosed |
| CN-118286431-A | Application of HIF-1 inhibitor britannin in tumor stem cell elimination and tumor treatment | 山东大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-116687914-B | Medicine for treating non-alcoholic fatty liver | 山东师范大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-117388389-A | Composition and method for screening gastric ulcer resistant medicinal substances in three-ingredient manna powder | 山东省科学院生物研究所 | 2024-01-12 | — | — | CN | disclosed |
| CN-116898957-A | Application of phycocyanin in preparation of medicine for treating chronic obstructive pulmonary disease | 中国科学院烟台海岸带研究所 | 2023-10-20 | — | — | CN | disclosed |
| CN-116687914-A | Medicine for treating non-alcoholic fatty liver | 山东师范大学 | 2023-09-05 | — | — | CN | disclosed |
| US-20230226259-A1 | NANOFIBER CARDIAC PATCH AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-07-20 | — | — | US | disclosed |
| CN-115960829-A | Method for efficiently amplifying NK cells | 青岛思拓新源细胞医学有限公司 | 2023-04-14 | — | — | CN | disclosed |