SCHEMBL16677163

SCHEMBL16677163

C=C1C(=O)O[C@H]2C[C@@H](C)[C@@H]3[C@@H](OC(C)=O)C[C@H](O)[C@@]3(C)[C@@H](OC(C)=O)[C@H]12

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 4/20 0.59
▸ MAPT P10636 4/20 0.59
▸ HTT P42858 4/20 0.59
▸ RAB9A P51151 4/20 0.59
▸ MAPK1 P28482 3/20 0.59
▸ AGTR1 P30556 3/20 0.59
▸ GPR55 Q9Y2T6 3/20 0.59
▸ XBP1 P17861 3/20 0.59
▸ MDM2 Q00987 3/20 0.59
▸ PAX8 Q06710 1/20 0.59
▸ POLB P06746 2/20 0.48
▸ THRB P10828 1/20 0.48
▸ OPRK1 P41145 1/20 0.48
▸ RECQL P46063 1/20 0.48
▸ BLM P54132 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ TLR9 Q9NR96 1/20 0.48
▸ PTGS2 P35354 2/20 0.45
▸ TERT O14746 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29096257 1.00 NPC1 (0.59) NPC1MAPTHTTRAB9AMAPK1
SCHEMBL16639615 0.92 NPC1 (0.62) NPC1MAPTHTTRAB9AMAPK1
Chamissonolide SCHEMBL23601535 0.91 NPC1 (0.52) NPC1MAPTHTTRAB9AMAPK1
SCHEMBL16641594 0.90 NPC1 (0.60) NPC1MAPTHTTRAB9AMAPK1
SCHEMBL16644430 0.89 NPC1 (0.59) NPC1MAPTHTTRAB9AMAPK1
SCHEMBL20376172 0.89 NPC1 (0.57) NPC1MAPTHTTRAB9AMAPK1
Inuchinenolide C SCHEMBL28264096 0.84 NPC1 (0.51) NPC1MAPTHTTRAB9AMAPK1
SCHEMBL16639616 0.82 NPC1 (0.50) NPC1MAPTHTTRAB9AMAPK1
SCHEMBL20953522 0.76 NPC1 (0.47) NPC1MAPTHTTRAB9AMAPK1
Ergolide SCHEMBL28262978 0.75 PTGS2 (0.67) NPC1MAPTHTTRAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118286431-A Application of HIF-1 inhibitor britannin in tumor stem cell elimination and tumor treatment 山东大学 2024-07-05 — — CN claimed
US-20260026508-A1 Seed Treatment Formulations and Methods of Use PUNA BIO CORP (US) 2026-01-29 — — US disclosed
EP-3924113-B1 MECHANOCHEMICAL PROCESS SMART MAT PRINTING B V (NL) 2025-11-26 — — EP disclosed
EP-4554920-A1 SEED TREATMENT FORMULATIONS AND METHODS OF USE Puna Bio Corporation (US) 2025-05-21 — — EP disclosed
US-12210567-B2 Methods, systems, and media for determining playlist title coherence and quality GOOGLE LLC (US) 2025-01-28 — — US disclosed
CN-118286431-A Application of HIF-1 inhibitor britannin in tumor stem cell elimination and tumor treatment 山东大学 2024-07-05 — — CN disclosed
CN-118286431-A Application of HIF-1 inhibitor britannin in tumor stem cell elimination and tumor treatment 山东大学 2024-07-05 — — CN disclosed
CN-118286431-A Application of HIF-1 inhibitor britannin in tumor stem cell elimination and tumor treatment 山东大学 2024-07-05 — — CN disclosed
WO-2024118131-A1 METHODS, SYSTEMS, AND MEDIA FOR DETERMINING PLAYLIST TITLE COHERENCE AND QUALITY GOOGLE LLC (US) 2024-06-06 — — WO disclosed
US-20240176816-A1 METHODS, SYSTEMS, AND MEDIA FOR DETERMINING PLAYLIST TITLE COHERENCE AND QUALITY GOOGLE LLC 2024-05-30 — — US disclosed
CN-110678469-B Substituted pyrimidinium compounds and derivatives for combating animal pests 巴斯夫欧洲公司 2023-03-03 — — CN disclosed
WO-2022248842-A1 SILVER ALLOY PRODUCTION ARGENTIUM INTERNATIONAL LIMITED (GB) 2022-12-01 — — WO disclosed
CN-115175996-A Novel type VI CRISPR enzymes and systems 博德研究所 2022-10-11 — — CN disclosed
CN-108348581-B Insulin immunoglobulin fusion proteins 斯克利普斯研究所 2022-07-01 — — CN disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 — — CN disclosed
US-20220058504-A1 AUTOCLASSIFICATION OF PRODUCTS USING ARTIFICIAL INTELLIGENCE ACCENTURE GLOBAL SOLUTIONS LIMITED (IE) 2022-02-24 — — US disclosed
US-10273220-B2 Derivative of Inula lineariifolia lactone A SHANXI ZHENDONG LEADING BIOTECHNOLOGY CO., LTD. (TW) 2019-04-30 — — US disclosed
EP-3345896-A1 DERIVATIVE OF INULA LINEARIIFOLIA LACTONE A Shanxi Zhendong Leading Biotechnology Co., Ltd. (CN) 2018-07-11 — — EP disclosed
EP-2865379-A1 APPLICATION OF INULA LINEARIIFOLIA LACTONE A IN PREPARATION OF MEDICINE FOR TREATING MULTIPLE SCLEROSIS SHANXI ZHENDONG PILOT BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) 2015-04-29 — — EP disclosed
EP-2865380-A1 APPLICATION OF INULA LINEARIIFOLIA LACTONE A IN PREPARATION OF MEDICINE FOR TREATING MYOCARDITIS The Second Military Medical University (CN) 2015-04-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10273220-B2 Derivative of Inula lineariifolia lactone A INMT, SIRT5, INPP5A NPC1 3040/4885MAPT 836/4885HTT 3528/4885
US-20260026508-A1 Seed Treatment Formulations and Methods of Use PGLS, GNE, GALE NPC1 4274/4885MAPT 356/4885HTT 1116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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