Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 6/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721017 | 0.83 | RXRA (0.45) | GRM5MEN1KMT2A | |
| SCHEMBL24721725 | 0.80 | SMN1; SMN2 (0.46) | GRM5 | |
| SCHEMBL23601592 | 0.77 | L3MBTL1 (0.46) | PGRGRM5FYNCLK4DYRK1B | |
| SCHEMBL23561017 | 0.75 | GRM5 (0.54) | GRM5MEN1KMT2A | |
| SCHEMBL23601598 | 0.74 | ALDH1A1 (0.49) | L3MBTL1MEN1KMT2A | |
| SCHEMBL23602041 | 0.73 | F10 (0.52) | L3MBTL1MEN1KMT2A | |
| SCHEMBL13284168 | 0.73 | L3MBTL1 (0.67) | PGRFYNCLK4DYRK1BL3MBTL1 | |
| SCHEMBL23576667 | 0.72 | RAB9A (0.44) | GRM5L3MBTL1 | |
| SCHEMBL22553962 | 0.72 | RAB9A (0.44) | GRM5 | |
| SCHEMBL22554331 | 0.72 | GRM5 (0.40) | PGRGRM5BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |