Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601598 | 0.91 | ALDH1A1 (0.49) | L3MBTL1F10TSHRTP53 | |
| SCHEMBL23602041 | 0.90 | F10 (0.52) | L3MBTL1F10TNIKTSHRTP53 | |
| SCHEMBL9564052 | 0.82 | L3MBTL1 (0.62) | L3MBTL1ALOX5 | |
| SCHEMBL621943 | 0.81 | ALDH1A1 (0.49) | L3MBTL1TSHR | |
| SCHEMBL13284168 | 0.81 | L3MBTL1 (0.67) | L3MBTL1PGRPARP10PARP11FYN | |
| SCHEMBL24721515 | 0.81 | BCL2 (0.49) | F10ALOX5BACE1 | |
| SCHEMBL23601594 | 0.79 | PARP10 (0.48) | PGRPARP10PARP11FYNCLK4 | |
| SCHEMBL23601603 | 0.79 | DRD2 (0.44) | L3MBTL1PGRPARP10PARP11FYN | |
| SCHEMBL2710657 | 0.77 | ALOX5 (0.48) | ALOX5TSHRTP53 | |
| SCHEMBL23601593 | 0.77 | PGR (0.50) | L3MBTL1PGRPARP10PARP11FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |