SCHEMBL23601671

SCHEMBL23601671

Cc1cc(F)cc(N(CC(F)(F)F)c2nc3nnc(C)n3c3cc(Cl)ccc23)c1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576716 0.91
SCHEMBL29909648 0.91
SCHEMBL23576702 0.83
SCHEMBL23601241 0.75 SMN1; SMN2 (0.35) MAT2A
SCHEMBL24808653 0.74 MAT2A (0.52) MAT2A
SCHEMBL29909179 0.74
SCHEMBL23601675 0.72 MAT2A (0.38) MAT2A
SCHEMBL23601672 0.72 MAPT (0.35)
SCHEMBL23601469 0.72 NQO2 (0.32)
SCHEMBL23601586 0.72 SMN1; SMN2 (0.35) MAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021130638-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2021-07-01 WO disclosed